Evidence map›Paper›PMID 33206308›Full record

ArticleBiometals : an international journal on the role of metal ions in biology, biochemistry, and medicine2021

Cardio-protective effects of a dioxidovanadium(V) complex in male sprague-dawley rats with streptozotocin-induced diabetes.

Bonisiwe Mbatha, Andile Khathi, Ntethelelo Sibiya, Irvin Booysen, Patrick Mangundu, Phikelelani Ngubane

Abstract read
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In one paragraph

Article in Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
0.6field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it, 9 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Exploring the Biological Effects of Anti-Diabetic Vanadium Compounds in the Liver, Heart and Brain.Diabetes, metabolic syndrome and obesity : targets and therapy · 2024
    Review
  5. Article
  6. Heteroleptic oxidovanadium(IV)-malate complex improves glucose uptake in HepG2 and enhances insulin action in streptozotocin-induced diabetic rats.Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Bonisiwe MbathaSchool of Laboratory Medicine and Medical Sciences, University of KwaZulu Natal, Durban, South Africa. mbathab3@ukzn.ac.za.
Andile KhathiSchool of Laboratory Medicine and Medical Sciences, University of KwaZulu Natal, Durban, South Africa.
Ntethelelo SibiyaPharmacology Division, Faculty of Pharmacy, Rhodes University, Grahamstown, South Africa.
Irvin BooysenSchool of Chemistry and Physics, College of Agricultural and Environmental Sciences, University of KwaZulu-Natal, Pietermaritzburg, South Africa.
Patrick MangunduSchool of Chemistry and Physics, College of Agricultural and Environmental Sciences, University of KwaZulu-Natal, Pietermaritzburg, South Africa.
Phikelelani NgubaneSchool of Laboratory Medicine and Medical Sciences, University of KwaZulu Natal, Durban, South Africa.
University of KwaZulu-Natal · ZARhodes University · ZA

Funding

College of Health Sciences Scholarship 210551793
6 · The paper itself

Abstract

Cardiovascular complications are among the leading causes of morbidity and mortality in diabetes mellitus (DM). Despite the anti-hyperglycemic effects of various anti-diabetic therapeutic agents like insulin, some of these drugs are implicated in precipitating cardiovascular dysfunction. There is therefore an imperative need to seek alternative drugs that may ameliorate these complications. Accordingly, the aim of the study was to investigate the effects of a dioxidovanadium (V) complex, cis-[VO

Indexed as

AnimalsCoordination ComplexesDiabetes Mellitus, ExperimentalDose-Response Relationship, DrugHypoglycemic AgentsMaleModels, MolecularProtective AgentsRatsRats, Sprague-DawleyStreptozocinVanadium CompoundsCoordination ComplexesHypoglycemic AgentsProtective AgentsStreptozocinVanadium CompoundsFibrosisHyperglycaemiaOxidative stressStreptozotocinVanadium

Identifiers

PMID33206308
OpenAlexW3106410685

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.