ArticleBiological trace element research2021
Chromium Exposure Causes Structural Aberrations of Erythrocytes, Gills, Liver, Kidney, and Genetic Damage in Striped Catfish Pangasianodon hypophthalmus.
Article in Biological trace element research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
30 citing papers in PubMed, 99 citations in OpenAlex.
- Protective role of probiotics or Spirulina platensis supplementation against mercury-induced hematological, histopathological, and antioxidant-immune gene dysregulation in Nile Tilapia (Oreochromis niloticus).Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine · 2026Article
- Behavioral, Hematological, Biochemical, Antioxidant, Histopathological and Micronuclear Abnormality in the Erythrocytes of Ctenopharyngodon idella Exposed to Chromium Chloride Toxicity.Biological trace element research · 2026Article
- Remediating effects of coral fossils on hematobiochemical, histo accumulation and organ histomorphological changes in Chromium intoxicated broilers.Poultry science · 2026Article
- Heavy-metal pollution in the Jhelum River (Pakistan) alters hematological and biochemical biomarkers and drives tissue bioaccumulation in Wallago attu.Biological trace element research · 2026Article
- Co-exposure to Hexavalent Chromium and Polyamide Microplastics Alters Growth, Hematology, Histopathology of Tissues and Immune Genes Expression in Striped Catfish (Pangasianodon hypophthalmus).Biological trace element research · 2026Article
- Dietary Spirulina Ameliorates Arsenic-Induced Toxicity in Nile Tilapia, Oreochromis niloticus.Veterinary medicine and science · 2026Article
- Mechanism of Liver Injury Induced by CrAnimals : an open access journal from MDPI · 2026Article
- Combined Effects of Microplastics and Mercury on Growth, Hematology, Tissue Morphology, GH/IGF Axis, and Antioxidant-Immune Responses in Nile Tilapia.Journal of toxicology · 2026Article
- Integrating hematological profile and biomarker analysis for metals and metalloids ecotoxicological assessment on Wallago catfish and Indian carp health in Head Siphon, Mailsi, Pakistan.Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine · 2025Article
- Perspective on health and ecological risk assessments of potentially toxic metal(loid)s using aquatic biodiversity as biomonitoring indicators.Toxicology reports · 2025Review
- Therapeutic Potential of Aloe vera and Aloe vera Fabricated Silver Nanoparticles on Reproductive Function in Male Mice Exposed to Hexavalent Chromium.Cell biochemistry and biophysics · 2025Article
- Ameliorative effects of coriander extract supplementation in mitigating nickel toxicity in grass carp (Ctenopharyngodon idella).Scientific reports · 2025Article
- Fate and Effects of Heavy Metals in Fishes: Antioxidant Defense System, miRNA/Gene Expression Response, and Histopathological Reproductive Manifestations.Biological trace element research · 2025Review
- Regime Shifts in Microbial and Water Quality Dynamics in Red Tilapia Ponds.Microorganisms · 2025Article
- The combined effect of cadmium and copper induces bioaccumulation, and toxicity and disrupts the antioxidant enzymatic activities of goldfish (Toxicology reports · 2025Article
- Hexavalent chromium (CrFish physiology and biochemistry · 2025Article
- Evaluation of Aflatoxins and Heavy Metals Exposure in the Local Feeds of Fish and Shrimp in Bangladesh.Biological trace element research · 2025Article
- The protective effect of various forms ofFrontiers in nutrition · 2025Article
- Anti-Oxidative and Anti-Apoptotic Oligosaccharides fromPharmaceuticals (Basel, Switzerland) · 2024Article
- Human Health Risk Assessment due to the Incidence of Heavy Metals in Different Commercial Feeds Used for the Culturing of Biofloc Fish (Nile tilapia: Oreochromis niloticus).Biological trace element research · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Heavy metal pollution due to anthropogenic activities poses a great threat to aquatic organisms. The present study was conducted to evaluate the cytotoxic and genotoxic effects of hexavalent chromium (potassium dichromate) on hemato-biochemical, histo-pathological, and genetical changes in striped catfish Pangasianodon hypophthalmus. Three sub-lethal doses (0.8, 1.6, and 3.2 mg/L) of chromium (Cr) were selected and fish were exposed in vivo contrasting with a control (0 mg/L) for 30 days. The study revealed that various hemato-biochemical parameters showed a significant decrease in hemoglobin (Hb), red blood cells (RBCs), and blood glucose content, whereas white blood cells (WBCs) significantly increased in Cr exposed fish. Frequencies of all forms of structural abnormalities of erythrocytes (erythrocytic cellular abnormalities; ECA, erythrocytic nuclear abnormalities; ENA and erythroblasts; Ebs) were significantly increased in higher two test concentrations (1.6 and 3.2 mg/L) when compared to control. Differential leucocyte count exhibited significant increase in neutrophil and decrease in lymphocytes in the highest Cr treated group. The severity of various histo-pathological changes in the gills, liver, and kidney were increased considerably with the increase of Cr concentrations. Similarly, the amount of DNA (ng/μl) decreased significantly in blood and tissues of different vital organs where the liver showed the highest decline compared to control in a concentration-dependent manner. Taken altogether, P. hypophthalmus is susceptible to Cr and can be used as a bio-indicator to assess aquatic metal pollution.
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Registered trials
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