Evidence map›Paper›PMID 33206286›Full record

ArticleCellular and molecular neurobiology2022

Recovery of Human Embryonic Stem Cells-Derived Neural Progenitors Exposed to Hypoxic-Ischemic-Reperfusion Injury by Indirect Exposure to Wharton's Jelly Mesenchymal Stem Cells Through Phosphatidyl-inositol-3-Kinase Pathway.

Sowmithra Sowmithra, Nishtha Kusum Jain, Ramesh Bhonde, Indrani Datta

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Cellular and molecular neurobiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.1field-weighted citation impact, top 49% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Sowmithra SowmithraDepartment of Biophysics, National Institute of Mental Health and Neurosciences, Institute of National Importance, Hosur Road, P.B. No. 2900, Bengaluru, 560029, Karnataka, India.
Nishtha Kusum JainDepartment of Biophysics, National Institute of Mental Health and Neurosciences, Institute of National Importance, Hosur Road, P.B. No. 2900, Bengaluru, 560029, Karnataka, India.
Ramesh BhondeDr D.Y. Patil University (DPU), Pune, 411018, India.
Indrani DattaDepartment of Biophysics, National Institute of Mental Health and Neurosciences, Institute of National Importance, Hosur Road, P.B. No. 2900, Bengaluru, 560029, Karnataka, India. indranidatta.nimhans@gmail.com.ORCID http://orcid.org/0000-0001-8864-473X
National Institute of Mental Health and Neurosciences · IND.Y. Patil University · IN

Funding

Council for Science and Industrial Research 37/(1614)/13/EMR-II
6 · The paper itself

Abstract

Increasing evidence suggests that mesenchymal stem cells(MSCs) have beneficial effects in hypoxic ischemic reperfusion injury, but the underlying mechanisms are unclear. Here, we first examined the effect of OGD reperfusion injury on the vulnerability of human NPs derived from human embryonic stem cells (hESCs) with regard to cell survival and oxidative stress. Cellular deregulation was assessed by measuring glutathione levels, basal calcium and intracellular calcium [Ca

Indexed as

Human Embryonic Stem CellsMesenchymal Stem CellsReperfusion InjuryWharton JellyHumansInositolPhosphatidylinositol 3-KinasePhosphatidylinositol 3-KinasesInositolPhosphatidylinositol 3-KinasePhosphatidylinositol 3-KinasesGlial progenitor populationIntracellular calciumIn vitro HIE modelMigration potentialOxidative stress susceptibilityOxygen glucose deprivation and reperfusionProliferationPSA-NCAMUmbilical cord-derived MSCs

Identifiers

PMID33206286
PMCPMC11441300
OpenAlexW3099653347

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.