Evidence map›Paper›PMID 33206263›Full record

ArticleAIDS and behavior2021

Early ART Initiation Improves HIV Status Disclosure and Social Support in People Living with HIV, Linked to Care Within a Universal Test and Treat Program in Rural South Africa (ANRS 12249 TasP Trial).

Marion Fiorentino, Marie Nishimwe, Camelia Protopopescu, Collins Iwuji, Nonhlanhla Okesola, Bruno Spire, Joanna Orne-Gliemann, Nuala McGrath, Deenan Pillay, François Dabis and 3 more

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In one paragraph

Article in AIDS and behavior, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.2field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 17 citations in OpenAlex.

  1. Trial
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  6. Significance of initiating antiretroviral therapy in the early stage of HIV infection.Zhejiang da xue xue bao. Yi xue ban = Journal of Zhejiang University. Medical sciences · 2022
    Article
  7. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 5 institutions in 3 countries.

Marion Fiorentino *Aix Marseille Univ, UMR912 - INSERM, IRD, SanteRCom, SESSTIM, Sciences Economiques & Sociales de la Santé & Traitement de L'Information Médicale, Faculté de Médecine, 27 bd Jean Moulin, 13005, Marseille, France. marion.fiorentino@inserm.fr.ORCID http://orcid.org/0000-0002-1615-4579
Marie Nishimwe *Aix Marseille Univ, UMR912 - INSERM, IRD, SanteRCom, SESSTIM, Sciences Economiques & Sociales de la Santé & Traitement de L'Information Médicale, Faculté de Médecine, 27 bd Jean Moulin, 13005, Marseille, France.
Camelia ProtopopescuAix Marseille Univ, UMR912 - INSERM, IRD, SanteRCom, SESSTIM, Sciences Economiques & Sociales de la Santé & Traitement de L'Information Médicale, Faculté de Médecine, 27 bd Jean Moulin, 13005, Marseille, France.
Collins IwujiAfrica Health Research Institute, Durban, South Africa.
Nonhlanhla OkesolaAfrica Health Research Institute, Durban, South Africa.
Bruno SpireAix Marseille Univ, UMR912 - INSERM, IRD, SanteRCom, SESSTIM, Sciences Economiques & Sociales de la Santé & Traitement de L'Information Médicale, Faculté de Médecine, 27 bd Jean Moulin, 13005, Marseille, France.
Joanna Orne-GliemannUniversity of Southampton, Southampton, UK.
Nuala McGrathAfrica Health Research Institute, Durban, South Africa.
Deenan PillayAfrica Health Research Institute, Durban, South Africa.
François DabisINSERM, UMR1219 Bordeaux Population Health Research Center, Université de Bordeaux, Bordeaux, France.
Joseph LarmarangeCeped UMR 196, Université Paris Descartes Inserm, Paris, France.
Sylvie BoyerAix Marseille Univ, UMR912 - INSERM, IRD, SanteRCom, SESSTIM, Sciences Economiques & Sociales de la Santé & Traitement de L'Information Médicale, Faculté de Médecine, 27 bd Jean Moulin, 13005, Marseille, France.
ANRS 12249 TaSP Study Group
Inserm · FRAfrica Health Research Institute · ZADélégation Paris 5 · FRBrighton and Sussex Medical School · GBUniversité de Bordeaux · FR

Funding

Agence Nationale de Recherches sur le Sida et les Hépatites Virales ANRS 12249 TasP trial
6 · The paper itself

Abstract

We investigated the effect of early antiretroviral treatment (ART) initiation on HIV status disclosure and social support in a cluster-randomized, treatment-as-prevention (TasP) trial in rural South Africa. Individuals identified HIV-positive after home-based testing were referred to trial clinics where they were invited to initiate ART immediately irrespective of CD4 count (intervention arm) or following national guidelines (control arm). We used Poisson mixed effects models to assess the independent effects of (a) time since baseline clinical visit, (b) trial arm, and (c) ART initiation on HIV disclosure (n = 182) and social support (n = 152) among participants with a CD4 count > 500 cells/mm

Indexed as

Anti-HIV AgentsHIV InfectionsDisclosureHumansSocial SupportSouth AfricaAnti-HIV AgentsEarly antiretroviral treatmentHIVHIV status disclosureSocial supportSouth africaTest and treat

Identifiers

PMID33206263
OpenAlexW3099634890

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.