Evidence map›Paper›PMID 33205751›Full record

ArticleeLife2020

Evolutionary stasis of the pseudoautosomal boundary in strepsirrhine primates.

Rylan Shearn, Alison E Wright, Sylvain Mousset, Corinne Régis, Simon Penel, Jean-François Lemaitre, Guillaume Douay, Brigitte Crouau-Roy, Emilie Lecompte, Gabriel Ab Marais

Open access · goldAbstract read
In one paragraph

Article in eLife, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.4field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 13 citations in OpenAlex.

  1. Article
  2. Sex Chromosome Evolution: Hallmarks and Question Marks.Molecular biology and evolution · 2024
    Review
  3. Article
  4. Article
  5. Article
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  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 4 countries.

Rylan ShearnLaboratoire Biométrie et Biologie Evolutive, CNRS / Univ. Lyon 1, Villeurbanne, France.
Alison E WrightDepartment of Animal and Plant Sciences, University of Sheffield, Sheffield, United Kingdom.
Sylvain MoussetLaboratoire Biométrie et Biologie Evolutive, CNRS / Univ. Lyon 1, Villeurbanne, France.
Corinne RégisLaboratoire Biométrie et Biologie Evolutive, CNRS / Univ. Lyon 1, Villeurbanne, France.
Simon PenelLaboratoire Biométrie et Biologie Evolutive, CNRS / Univ. Lyon 1, Villeurbanne, France.
Jean-François LemaitreLaboratoire Biométrie et Biologie Evolutive, CNRS / Univ. Lyon 1, Villeurbanne, France.
Guillaume DouayZoo de Lyon, Lyon, France.
Brigitte Crouau-RoyLaboratoire Evolution et Diversité Biologique, CNRS / Univ. Toulouse, Toulouse, France.
Emilie LecompteLaboratoire Evolution et Diversité Biologique, CNRS / Univ. Toulouse, Toulouse, France.ORCID 0000-0002-5711-7395
Gabriel Ab MaraisLaboratoire Biométrie et Biologie Evolutive, CNRS / Univ. Lyon 1, Villeurbanne, France.ORCID 0000-0003-2134-5967
Université Claude Bernard Lyon 1 · FRCentre National de la Recherche Scientifique · FRUniversity of Sheffield · GB

Funding

Agence Nationale de la Recherche ANR-­‐12-­‐ BSV7-­‐0002-­‐04Agence Nationale de la Recherche ANR--12-- BSV7--0002--04
6 · The paper itself

Abstract

Sex chromosomes are typically comprised of a non-recombining region and a recombining pseudoautosomal region. Accurately quantifying the relative size of these regions is critical for sex-chromosome biology both from a functional and evolutionary perspective. The evolution of the pseudoautosomal boundary (PAB) is well documented in haplorrhines (apes and monkeys) but not in strepsirrhines (lemurs and lorises). Here, we studied the PAB of seven species representing the main strepsirrhine lineages by sequencing a male and a female genome in each species and using sex differences in coverage to identify the PAB. We found that during primate evolution, the PAB has remained unchanged in strepsirrhines whereas several recombination suppression events moved the PAB and shortened the pseudoautosomal region in haplorrhines. Strepsirrhines are well known to have much lower sexual dimorphism than haplorrhines. We suggest that mutations with antagonistic effects between males and females have driven recombination suppression and PAB evolution in haplorrhines.

Indexed as

Evolution, MolecularAnimalsFemaleMalePolymorphism, Single NucleotideSex ChromosomesSpecies SpecificityStrepsirhinievolutionary biologylemursprimatesrecombination suppressionsex chromosomessexual dimorphismsexually antagonistic mutations

Identifiers

PMID33205751
PMCPMC7717902
OpenAlexW3102564399

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.