Evidence map›Paper›PMID 33205495›Full record

ArticleThe International journal of eating disorders2021

Emotion dysregulation and suicidality in eating disorders.

Marianna Rania, Elin Monell, Arvid Sjölander, Cynthia M Bulik

Registry-linked trialOpen access · hybridAbstract read
In one paragraph

Article in The International journal of eating disorders, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06693089 (Metacognitive Interpersonal Therapy Across Transdiagnostic Eating Disorders Including Underweight), which is not on this map. Cited by 20 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 1 pooled it
2.4field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06693089 naactive not recruitingnot on this mapstarted 2024, after this paper: background citation

Metacognitive Interpersonal Therapy Across Transdiagnostic Eating Disorders Including Underweight: Study Protocol for a Single-arm Pilot Study

TypeinterventionalSponsorGLORIA FIORAVANTIRan2024 to 2026Enrolled64ConditionsEating Disorders, Maladaptive Personality Trait, Personality Disorder, Personality TraitArmsMIT-ED
3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 1 synthesis or guideline pooled it, 41 citations in OpenAlex.

  1. Pooled it
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  10. Metacognitive interpersonal therapy-eating disordersResearch in psychotherapy (Milano) · 2023
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  19. Emotion dysregulation and suicidality in eating disorders.The International journal of eating disorders · 2021
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 3 countries.

Marianna RaniaDepartment of Health Sciences, University Magna Graecia of Catanzaro, Catanzaro, Italy.ORCID 0000-0001-7742-7086
Elin MonellDepartment of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden.ORCID 0000-0002-3305-4844
Arvid SjölanderDepartment of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden.
Cynthia M BulikDepartment of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden.
Karolinska Institutet · SEUniversity of North Carolina at Chapel Hill · US

Funding

Eating Disorders Genetics Initiative (EDGI)R01MH120170 · NIMH · UNIV OF NORTH CAROLINA CHAPEL HILL · PI BULIK, CYNTHIA M · 2019 to 2023
$7.2M
Predicting Binge and Purge Episodes from Passive and Active Apple Watch Data Using a Dynamical Systems ApproachR01MH119084 · NIMH · UNIV OF NORTH CAROLINA CHAPEL HILL · PI BULIK, CYNTHIA M, BUTNER, JONATHAN · 2019 to 2022
$2.8M
Premorbid metabolism and growth in anorexia nervosa: A genetically informed exploration of riskR21MH115397 · NIMH · UNIV OF NORTH CAROLINA CHAPEL HILL · PI BULIK, CYNTHIA M, MICALI, NADIA · 2017 to 2018
$362k
NIMH NIH HHS R01 MH119084NIMH NIH HHS R01 MH120170NIMH NIH HHS R21 MH115397
6 · The paper itself

Abstract

objectiveSuicidality in eating disorders (EDs) is high, and identification of therapeutically targetable traits associated with past, current, and future suicidality is of considerable clinical importance. We examined overall and ED subtype-specific associations among suicidal ideation, suicide attempts, and general and specific aspects of emotion dysregulation in a large sample of individuals with ED, at presentation for treatment and 1-year follow-up.

methodUsing registry data from 2,406 patients, scores on the Difficulties in Emotion Dysregulation Scale (DERS) at initial registration were examined as predictors of recent suicidal ideation and self-report lifetime suicide attempts. Associations were examined in the full sample and in each ED subtype. In 406 patients, initial DERS scores were examined as predictors of suicidality at 1-year follow-up.

resultsOverall DERS was associated with suicidal ideation and suicide attempts, even when adjusting for ED psychopathology and current depression. Perceived lack of emotion regulation strategies showed unique associations with suicidal ideation and suicide attempts, both in the full sample and in most ED subtypes. Initial DERS was also associated with follow-up suicidal ideation and suicide attempts, although this association did not remain when adjusting for past suicidality. DISCUSSION: Results suggest that emotion dysregulation may be a potential mechanism contributing to suicidality in EDs, beyond the effects of ED psychopathology and current depression. Although the prevalence of suicidality differs across ED subtypes, emotion dysregulation may represent a risk trait for future suicidality that applies transdiagnostically. Results support addressing emotion dysregulation in treatment in order to reduce suicidality.

Indexed as

Feeding and Eating DisordersSuicideAdolescentChildEmotionsFemaleHumansRisk FactorsSuicidal IdeationSuicide, AttempteddepressionDERSeating disordersemotion dysregulationsuicidal ideationsuicide attemptssuicide risk

Identifiers

PMID33205495
PMCPMC7984062
OpenAlexW3099946226

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.