ArticleAging clinical and experimental research2021
The Emergency Surgery Frailty Index (EmSFI): development and internal validation of a novel simple bedside risk score for elderly patients undergoing emergency surgery.
Article in Aging clinical and experimental research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05226221 (Mortality and Morbidity in Emergency Gastrointestinal Surgery), which is not on this map. Cited by 21 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Mortality and Morbidity in Emergency Gastrointestinal Surgery: Comparison of Different Incidence of Interventions According to the ICD-9-CM Classification in Relation to the Age Groups
Who cites it
21 citing papers in PubMed, 27 citations in OpenAlex.
- The investigation of effect on foot plantar massage on functional recovery in older adults with general surgery, randomized clinical trial.Aging clinical and experimental research · 2024Trial
- Prevalence and outcomes of frailty in emergency laparotomy: a single-centre cohort study.European journal of trauma and emergency surgery : official publication of the European Trauma Society · 2026Article
- The Role of Emerging Immune-Inflammatory Indexes in the Preoperative Differentiation of Complicated and Uncomplicated Acute Appendicitis: A Single-Center Retrospective Analysis.Diagnostics (Basel, Switzerland) · 2025Article
- Assessment of frailty and inflammatory burden index as predictors of postoperative IAA in elderly appendectomy patients.BMC surgery · 2025Article
- Frailty diminishes functional outcome in patients with nonaneurysmal subarachnoid hemorrhage: a dual specialized neurovascular center analysis.Journal of neurology · 2025Article
- A Comparison of Machine Learning-Based Models and a Simple Clinical Bedside Tool to Predict Morbidity and Mortality After Gastrointestinal Cancer Surgery in the Elderly.Bioengineering (Basel, Switzerland) · 2025Article
- Review
- Clinical Impact of Sarcopenia in the Decision-Making Process for Patients with Acute Diverticulitis.Journal of clinical medicine · 2024Article
- Practice patterns and clinical outcomes in acute appendicitis differ in the elderly patient.European journal of trauma and emergency surgery : official publication of the European Trauma Society · 2024Observational
- The Emergency Surgery Frailty Index (EmSFI) in Elderly Patients with Acute Appendicitis: An External Validation of Prognostic Score.World journal of surgery · 2023Article
- Efficacy of blood parameters as indicators of the need for overdue urgent cholecystectomy in elderly patients with acute cholecystitis.Ulusal travma ve acil cerrahi dergisi = Turkish journal of trauma & emergency surgery : TJTES · 2023Article
- The Emergency Surgery Frailty Index (EmSFI) in Elderly Patients with Acute Appendicitis: An External Validation of Prognostic Score.World journal of surgery · 2023Observational
- An ensemble machine learning approach to predict postoperative mortality in older patients undergoing emergency surgery.BMC geriatrics · 2023Article
- Editorial: Surgical outcomes in acute care surgery: should we introduce the concept of time-critical condition?Frontiers in surgery · 2023Article
- Outcomes of emergency laparoscopy in the elderly.Annals of the Royal College of Surgeons of England · 2022Observational
- Clinical-pathological features and treatment of acute appendicitis in the very elderly: an interim analysis of the FRAILESEL Italian multicentre prospective study.European journal of trauma and emergency surgery : official publication of the European Trauma Society · 2022Article
- Identifying relationships between kinesiophobia, functional level, mobility, and pain in older adults after surgery.Aging clinical and experimental research · 2022Article
- Metabolic Syndrome (MetS), Systemic Inflammatory Response Syndrome (SIRS), and Frailty: Is There any Room for Good Outcome in the Elderly Undergoing Emergency Surgery?Frontiers in surgery · 2022Article
- Gastro-intestinal emergency surgery: Evaluation of morbidity and mortality. Protocol of a prospective, multicenter study in Italy for evaluating the burden of abdominal emergency surgery in different age groups. (The GESEMM study).Frontiers in surgery · 2022Article
- A systematic review of predictive accuracy via c-statistic of preoperative frailty tests for extended length of stay, post-operative complications, and mortality.Saudi journal of anaesthesiaReview
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Authors and funding
11 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundFrailty assessment has acquired an increasing importance in recent years and it has been demonstrated that this vulnerable profile predisposes elderly patients to a worse outcome after surgery. Therefore, it becomes paramount to perform an accurate stratification of surgical risk in elderly undergoing emergency surgery. STUDY
design1024 patients older than 65 years who required urgent surgical procedures were prospectively recruited from 38 Italian centers participating to the multicentric FRAILESEL (Frailty and Emergency Surgery in the Elderly) study, between December 2016 and May 2017. A univariate analysis was carried out, with the purpose of developing a frailty index in emergency surgery called "EmSFI". Receiver operating characteristic curve analysis was then performed to test the accuracy of our predictive score.
results784 elderly patients were consecutively enrolled, constituting the development set and results were validated considering further 240 consecutive patients undergoing colorectal surgical procedures. A logistic regression analysis was performed identifying different EmSFI risk classes. The model exhibited good accuracy as regard to mortality for both the development set (AUC = 0.731 [95% CI 0.654-0.772]; HL test χ
conclusionsThe validated EmSFI represents a reliable and time-sparing tool, despite its discriminative value decreased regarding complications. Thus, further studies are needed to investigate specifically surgical settings, validating the EmSFI prognostic role in assessing the procedure-related morbidity risk.
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