Evidence map›Paper›PMID 33205025›Full record

ReviewiScience2020

Histone Demethylases as Counterbalance to H3K27me3 Silencing in Plants.

Pedro Crevillén

Open access · goldAbstract readReview
In one paragraph

Review in iScience, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
1.7field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 35 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author at 1 institution in 1 country.

Pedro CrevillénCentro de Biotecnología y Genómica de Plantas (CBGP), Universidad Politécnica de Madrid (UPM) - Instituto Nacional de Investigación y Tecnología Agraria y Alimentaria (INIA), 28223 Pozuelo de Alarcón (Madrid), Spain.
Universidad Politécnica de Madrid · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The universal importance of epigenetic regulation has become explicit over the last decade. There is now a detailed understanding of the molecular signatures and chromatin-modifying enzymes determining epigenetic regulation. For example, the trimethylation of lysine 27 at histone H3 by Polycomb complexes is a hallmark of silenced gene expression conserved across animal and plant kingdoms. The repressive activity of Polycomb complexes is balanced by the histone demethylase activity of Jumonji C-domain proteins. There has been a lot of research on Polycomb functions and H3K27 methylation; however, until recently, little was known about the role of histone H3K27 demethylases. Here, we review the role of Jumonji C-domain proteins from the plant development perspective. We will recall the history of histone lysine demethylation and explore the recent advances on the H3K27 demethylases in plant biology. Conserved and novel genomic functions of these epigenetic regulators will be discussed.

Indexed as

Biological SciencesPlant BiologyPlant Development

Identifiers

PMID33205025
PMCPMC7649346
OpenAlexW3093506171

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.