Evidence map›Paper›PMID 33205024›Full record

ArticleiScience2020

Comparative Study of Curvature Sensing Mediated by F-BAR and an Intrinsically Disordered Region of FBP17.

Maohan Su, Yinyin Zhuang, Xinwen Miao, Yongpeng Zeng, Weibo Gao, Wenting Zhao, Min Wu

Abstract read
In one paragraph

Article in iScience, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed.

  1. Article
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  10. Coaching ribosome biogenesis from the nuclear periphery.bioRxiv : the preprint server for biology · 2024
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  12. Article
  13. Competition and Synergy of Arp2/3 and Formins in Nucleating Actin Waves.bioRxiv : the preprint server for biology · 2023
    Article
  14. Article
  15. Article
  16. Review
  17. Article
  18. Article
  19. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Maohan SuDepartment of Cell Biology, Yale University School of Medicine, 333 Cedar Street, New Haven, CT 06520-8002, USA.
Yinyin ZhuangDepartment of Cell Biology, Yale University School of Medicine, 333 Cedar Street, New Haven, CT 06520-8002, USA.
Xinwen MiaoSchool of Chemical and Biomedical Engineering, Nanyang Technological University, Singapore, 637457.
Yongpeng ZengSchool of Chemical and Biomedical Engineering, Nanyang Technological University, Singapore, 637457.
Weibo GaoSchool of Physics and Mathematical Science, Nanyang Technological University, Singapore, 637371.
Wenting ZhaoSchool of Chemical and Biomedical Engineering, Nanyang Technological University, Singapore, 637457.
Min WuDepartment of Cell Biology, Yale University School of Medicine, 333 Cedar Street, New Haven, CT 06520-8002, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Membrane curvature has emerged as an intriguing physical principle underlying biological signaling and membrane trafficking. The CIP4/FBP17/Toca-1 F-BAR subfamily is unique in the BAR family because its structurally folded F-BAR domain does not contain any hydrophobic motifs that insert into membrane. Although widely assumed so, whether the banana-shaped F-BAR domain alone can sense curvature has never been experimentally demonstrated. Using a nanobar-supported lipid bilayer system, we found that the F-BAR domain of FBP17 displayed minimal curvature sensing

Indexed as

Biological SciencesBiophysicsCell Biology

Identifiers

PMID33205024
PMCPMC7649350

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.