ArticleiScience2020
Single-Cell Profiling Reveals Divergent, Globally Patterned Immune Responses in Murine Skin Inflammation.
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Article in iScience, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 47 papers.
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47citing papers in PubMed
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Who cites it
47 citing papers in PubMed.
- Ucenprubart is an agonistic antibody to CD200R with the potential to treat inflammatory skin disease: preclinical development and a phase 1 clinical study.Nature communications · 2025Trial
- Targeting Macrophage STING O-GlcNAcylation via Small-Molecule Allosteric Modulation for Psoriasis Therapy.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- A stretch-responsive fibroblast program promotes epidermal stem cell self-renewal during skin expansion.Nature communications · 2026Article
- Transcription-independent induction of rapid-onset senescence is integral to healing.Nature cell biology · 2026Article
- Sensitizer-Induced Basophils Accelerate Skin Re-Epithelialization via IL-4/IL-13-Mediated Macrophage Polarization.Allergy · 2026Article
- Article
- singIST: An integrative method for comparative single-cell transcriptomics between disease models and humans.PLoS computational biology · 2026Article
- Reevaluating the Imiquimod Model: A Barrier to Translational Progress in Psoriasis.The Journal of investigative dermatology · 2026Review
- TNFR2 is expressed by a discrete subset of epidermal T cells with an IL-17 gene signature during psoriasis.PloS one · 2026Article
- Skin-derived myeloid precursors and joint-resident fibroblasts spread psoriatic disease from skin to joints.Nature immunology · 2026Article
- Single-cell RNA sequencing reveals T and B cell-related immune features in foot and mouth disease virus-infected mice.Virulence · 2025Article
- Single cell transcriptomics of human psoriasis and epidermal specific Ube2l3 deficient mice highlight CXCL16/CXCR6 involvement in psoriasis development.Nature communications · 2025Article
- Comparative Single-Cell Transcriptome Analysis of c-Met Receptor Expressing and Non-Expressing Projection Neurons in the Developing Frontal and Visual Cortices.Developmental neuroscience · 2025Article
- An oncolytic herpes simplex virus armed with IL-12 for treatment of preclinical glioblastoma.Molecular therapy. Oncology · 2025Article
- HEB collaborates with TCR signaling to upregulatebioRxiv : the preprint server for biology · 2025Article
- TNFR2 is Expressed by a Discrete Subset of Epidermal γδ T Cells with an IL-17 Gene Signature during Psoriasis.bioRxiv : the preprint server for biology · 2025Article
- A basophil-fibroblast pro-inflammatory axis fuels type 2 skin inflammation.Cell reports · 2025Article
- IL-33-primed NLRP3 inflammasome in basophils drives IL-1β production and initiates atopic dermatitis inflammation.Cell death discovery · 2025Article
- Article
- In vivo AAV-SB-CRISPR screens of tumor-infiltrating primary NK cells identify genetic checkpoints of CAR-NK therapy.Nature biotechnology · 2025Article
Corrections and comments
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Authors and funding
25 authors.
Yale LiuDepartment of Dermatology, University of California, San Francisco, San Francisco, CA, USA.
Christopher CookDepartment of Dermatology, University of California, San Francisco, San Francisco, CA, USA.
Andrew J SedgewickImmunityBio Inc, Culver City, CA, USA.
Shuyi ZhangDepartment of Physics, Carl R. Woese Institute for Genomic Biology, University of Illinois at Urbana-Champaign, Champaign, IL, USA.
Marlys S FassettDepartment of Dermatology, University of California, San Francisco, San Francisco, CA, USA.
Roberto R Ricardo-GonzalezDepartment of Dermatology, University of California, San Francisco, San Francisco, CA, USA.
Paymann HarirchianDepartment of Dermatology, University of California, San Francisco, San Francisco, CA, USA.
Sakeen W KashemDepartment of Dermatology, University of California, San Francisco, San Francisco, CA, USA.
Sho HanakawaDepartment of Dermatology, Kyoto University Graduate School of Medicine, Kyoto, Japan.
Jacob R LeisticoDepartment of Physics, Carl R. Woese Institute for Genomic Biology, University of Illinois at Urbana-Champaign, Champaign, IL, USA.
Jeffrey P NorthDepartment of Dermatology, University of California, San Francisco, San Francisco, CA, USA.
Mark A TaylorDepartment of Dermatology, University of California, San Francisco, San Francisco, CA, USA.
Wei ZhangDermatology Service, San Francisco Veterans Administration Health Care System, San Francisco, CA, USA.
Mao-Qiang ManDermatology Service, San Francisco Veterans Administration Health Care System, San Francisco, CA, USA.
Alexandra CharruyerDepartment of Dermatology, University of California, San Francisco, San Francisco, CA, USA.
Nadejda Beliakova-BethellDepartment of Medicine, University of California San Diego, La Jolla, CA 92093-0679, USA.
Stephen C BenzImmunityBio Inc, Culver City, CA, USA.
Ruby GhadiallyDermatology Service, San Francisco Veterans Administration Health Care System, San Francisco, CA, USA.
Theodora M MauroDermatology Service, San Francisco Veterans Administration Health Care System, San Francisco, CA, USA.
Daniel H KaplanDepartments of Dermatology and Immunology, University of Pittsburgh, Pittsburgh, PA, USA.
Kenji KabashimaDepartment of Dermatology, Kyoto University Graduate School of Medicine, Kyoto, Japan.
Jaehyuk ChoiDepartment of Dermatology, Northwestern School of Medicine, Chicago, IL, USA.
Jun S SongDepartment of Physics, Carl R. Woese Institute for Genomic Biology, University of Illinois at Urbana-Champaign, Champaign, IL, USA.
Raymond J ChoDepartment of Dermatology, University of California, San Francisco, San Francisco, CA, USA.
Jeffrey B ChengDepartment of Dermatology, University of California, San Francisco, San Francisco, CA, USA.
Funding
Predicting Transcriptional and Epigenetic Networks in Cancer from Sequencing DataR01CA163336 · NCI · UNIVERSITY OF ILLINOIS AT URBANA-CHAMPAIGN · PI Jun S Song · 2012 to 2026
$4.4MPathogenesis and Therapy of Ichthyosis in Disorders of Lipid MetabolismR01AR061106 · NIAMS · NORTHERN CALIFORNIA INSTITUTE/RES/EDU · PI MAURO, THEODORA M · 2012 to 2022
$3.3MElucidating the role of type 2 immunity in skin homeostasisK08AR075880 · NIAMS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI RICARDO-GONZALEZ, ROBERTO RAFAEL · 2019 to 2023
$888kInterleukin-31 at the neuroimmune interface of pruritus and dermatitisK08AR074556 · NIAMS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI FASSETT, MARLYS S · 2019 to 2023
$887kRole of DNA Methylation and Hydroxymethylation in Epidermal HomeostasisK08AR067243 · NIAMS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI CHENG, JEFFREY B · 2015 to 2019
$834kHIV reactivation from latency - role of CD4 T cell maturation phenotypeIK2BX002731 · VA · VA SAN DIEGO HEALTHCARE SYSTEM · PI BELIAKOVA-BETHELL, NADEJDA S · 2016 to 2020
–BLRD VA IK2 BX002731NCI NIH HHS R01 CA163336NIAMS NIH HHS K08 AR067243NIAMS NIH HHS K08 AR074556NIAMS NIH HHS K08 AR075880NIAMS NIH HHS R01 AR061106
Abstract
Inflammatory response heterogeneity has impeded high-resolution dissection of diverse immune cell populations during activation. We characterize mouse cutaneous immune cells by single-cell RNA sequencing, after inducing inflammation using imiquimod and oxazolone dermatitis models. We identify 13 CD45
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