Evidence map›Paper›PMID 33204813›Full record

ArticleAlzheimer's & dementia (Amsterdam, Netherlands)2020

Association between neurite metrics and tau/inflammatory pathology in Alzheimer's disease.

Daichi Sone, Yoko Shigemoto, Masayo Ogawa, Norihide Maikusa, Kyoji Okita, Harumasa Takano, Koichi Kato, Noriko Sato, Hiroshi Matsuda

Open access · goldAbstract read
In one paragraph

Article in Alzheimer's & dementia (Amsterdam, Netherlands), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
2.6field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 30 citations in OpenAlex.

  1. Brain microstructure mediates the relationship between Alzheimer's proteinopathies and memory.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2026
    Article
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  10. Brain communications · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 2 countries.

Daichi SoneIntegrative Brain Imaging Center National Center of Neurology and Psychiatry Tokyo Japan.ORCID https://orcid.org/0000-0001-9617-706X
Yoko ShigemotoIntegrative Brain Imaging Center National Center of Neurology and Psychiatry Tokyo Japan.
Masayo OgawaIntegrative Brain Imaging Center National Center of Neurology and Psychiatry Tokyo Japan.
Norihide MaikusaIntegrative Brain Imaging Center National Center of Neurology and Psychiatry Tokyo Japan.
Kyoji OkitaIntegrative Brain Imaging Center National Center of Neurology and Psychiatry Tokyo Japan.
Harumasa TakanoIntegrative Brain Imaging Center National Center of Neurology and Psychiatry Tokyo Japan.
Koichi KatoIntegrative Brain Imaging Center National Center of Neurology and Psychiatry Tokyo Japan.
Noriko SatoDepartment of Radiology National Center of Neurology and Psychiatry Tokyo Japan.
Hiroshi MatsudaIntegrative Brain Imaging Center National Center of Neurology and Psychiatry Tokyo Japan.
National Center of Neurology and Psychiatry · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionThe molecular mechanism of neurodegeneration, including tau and neurite complexity, is an important topic in Alzheimer's disease (AD) research.

methodsWe recruited 27 amyloid-positive individuals identified through

resultsIn the amyloid-positive participants, there were significant negative correlations between DISCUSSION: Tau and neuroinflammation in AD may reduce the neurite density and orientation dispersion, particularly in the mesial and lateral temporal lobes.

Indexed as

Alzheimer's diseasemolecular imagingneurodegenerationneuroinflammationorientation dispersion and density imagingtau

Identifiers

PMID33204813
PMCPMC7656172
OpenAlexW3099509655

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.