Evidence map›Paper›PMID 33204555›Full record

ArticleCase reports in oncological medicine2020

Successful Treatment by Surgery and Lenvatinib of a Patient with Adrenal Metastasis of Papillary Thyroid Cancer.

Hajime Nakamura, Kohichi Takada, Kazuyuki Murase, Hiroki Sakamoto, Naotaka Hayasaka, Kazuma Ishikawa, Yuki Ikeda, Makoto Yoshida, Satoshi Iyama, Ko Kobayashi and 6 more

Open access · goldAbstract readCase Reports
In one paragraph

Article in Case reports in oncological medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.4field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 1 institution in 1 country.

Hajime NakamuraDepartment of Medical Oncology, Sapporo Medical University School of Medicine, Japan.
Kohichi TakadaDepartment of Medical Oncology, Sapporo Medical University School of Medicine, Japan.ORCID https://orcid.org/0000-0002-1393-9442
Kazuyuki MuraseDepartment of Medical Oncology, Sapporo Medical University School of Medicine, Japan.
Hiroki SakamotoDepartment of Medical Oncology, Sapporo Medical University School of Medicine, Japan.
Naotaka HayasakaDepartment of Medical Oncology, Sapporo Medical University School of Medicine, Japan.
Kazuma IshikawaDepartment of Medical Oncology, Sapporo Medical University School of Medicine, Japan.
Yuki IkedaDepartment of Medical Oncology, Sapporo Medical University School of Medicine, Japan.
Makoto YoshidaDepartment of Medical Oncology, Sapporo Medical University School of Medicine, Japan.
Satoshi IyamaDepartment of Hematology, Sapporo Medical University School of Medicine, Japan.
Ko KobayashiDepartment of Urology, Sapporo Medical University School of Medicine, Japan.
Tetsuya ShindoDepartment of Urology, Sapporo Medical University School of Medicine, Japan.
Shintaro SugitaDepartment of Surgical Pathology, Sapporo Medical University School of Medicine, Japan.
Koji MiyanishiDepartment of Medical Oncology, Sapporo Medical University School of Medicine, Japan.
Masayoshi KobuneDepartment of Hematology, Sapporo Medical University School of Medicine, Japan.
Naoya MasumoriDepartment of Urology, Sapporo Medical University School of Medicine, Japan.
Junji KatoDepartment of Medical Oncology, Sapporo Medical University School of Medicine, Japan.
Sapporo Medical University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Papillary thyroid cancer (PTC) is considered an indolent cancer, but some PTC patients do present with distant metastases and treatment strategies for such patients are not well established. Recently, lenvatinib, an inhibitor of multiple tyrosine kinases, has been introduced to treat patients with advanced PTC but carries a risk of serious adverse events such as hemorrhage. Here, we report a PTC patient with a left adrenal metastasis and lenvatinib-induced hemorrhage who underwent successful surgical resection and was subsequently treated with a lower dose of lenvatinib. The patient has now been in a stable state with no adverse events for nearly two years. This case highlights the importance of surgical resection of metastatic PTC and subsequent lenvatinib therapy, even when the tumor is at an advanced stage.

Identifiers

PMID33204555
PMCPMC7661144
OpenAlexW3096988850

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.