ArticleThe World Allergy Organization journal2020
Allergy and immunology in young children of Japan: The JECS cohort.
Article in The World Allergy Organization journal, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 45 papers, 2 of them syntheses that pooled it.
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The trial behind it
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Who cites it
45 citing papers in PubMed, 2 syntheses or guidelines pooled it, 106 citations in OpenAlex.
- A Meta-Analysis of the Prevalence of Wheat Allergy Worldwide.Nutrients · 2023Pooled it
- Global patterns in anaphylaxis due to specific foods: A systematic review.The Journal of allergy and clinical immunology · 2021Pooled it
- Trial
- Hen's Egg Allergy: Immunological Mechanisms, Epidemiology, and Predictors of Persistence in Childhood.Allergy, asthma & immunology research · 2026Review
- Association of breastfeeding with caregiver-reported physician-diagnosed allergies in children: the Japan Environment and Children's Study.BMC pediatrics · 2026Article
- Environmental food allergen levels in the homes of 3-4-month-old infants: findings from the second phase Chiba study of mother and child health (2nd C-MACH).Scientific reports · 2026Article
- Barriers to Accurate Diagnosis of Infantile Atopic Dermatitis: Insights From a Survey of Pediatricians.The Journal of dermatology · 2026Article
- Article
- Association between maternal dietary isoflavone consumption during pregnancy and childhood food allergy in offspring: The Japan Environment and Children's study.Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology · 2026Article
- Article
- Parental Age and Childhood Allergy Risk.JAMA network open · 2026Article
- Overcoming anaphylactic severe cow's milk allergy with slow and low-dose oral immunotherapy: A 10-year path to tolerance.Asia Pacific allergy · 2025Article
- Symptoms of egg yolk-associated food protein-induced enterocolitis syndrome appear following prolonged cessation.JPGN reports · 2025Article
- Safer oral immunotherapy with very low-dose introduction for pediatric hen's egg allergy.The journal of allergy and clinical immunology. Global · 2025Article
- Non-immunoglobulin E-mediated gastrointestinal food allergies in children with Down syndrome: An epidemiological study.The World Allergy Organization journal · 2025Article
- Lung functions and IgE component sensitizations: Five wheezing phenotypes in adolescents from the T-Child study in Tokyo.The journal of allergy and clinical immunology. Global · 2025Article
- Allergens from wheat and wheat products: A comprehensive review on allergy mechanisms and modifications.Food chemistry: X · 2025Review
- Surveys on the prevalence of pediatric asthma in Japan: A comparison between the 1982, 1992, 2002, 2012, and 2022 surveys conducted in the same region using the same methodology (WJSAAC PhaseⅠ∼Ⅴ).The World Allergy Organization journal · 2025Article
- Article
- Relationship between maternal egg consumption during lactation and the risk of developing egg allergies in 12-month-old infants: A multicenter cohort study.Japan journal of nursing science : JJNS · 2025Article
Corrections and comments
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Authors and funding
12 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundCapturing epidemiological signatures is essential to document burdens of disease and to design health care services, including prevention measures, clinical interventions, and policies. There are large geographical and ethnic variations in the epidemiology of allergic and immunological diseases. Various data are available from North America and Europe, but the epidemiology of allergic and immunological diseases in Asia is not well documented.
objectiveTo characterize epidemiological signatures of allergic and immunological disease in young children in Japan.
methodsThis was a national, multicenter, prospective birth cohort study: Japan Environment and Children's Study (JECS). A general population of 103,060 women was enrolled during pregnancy. Allergic and immunological outcomes were assessed among young children using questionnaire data.
resultsThe prevalence of caregiver-reported immediate food allergy was 7.6%, 6.7%, and 4.9% at age 1, 2, and 3 years, respectively. Hen egg allergy was most common (5.4% prevalence at age 1 year) followed by allergies to cow milk and wheat. Several patterns of allergic symptom clusters were identified. Physician diagnosed, as reported by the caregiver, non-IgE mediated gastrointestinal food allergy affected 0.5% of infants. By contrast, caregiver-reported gastrointestinal food allergies affected 1.4% of children. Kawasaki disease affected 0.3% and 0.4% children, respectively, at age 1 and 3 years. Primary immunodeficiency disorders affected 0.005% children at age 3 years.
conclusionThese data provide important epidemiological signatures of allergy and immunology in young Japanese children including the age-specific prevalence of allergic disease, Kawasaki disease, and primary immune deficiency.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.