Evidence map›Paper›PMID 33204114›Full record

ReviewJournal of asthma and allergy2020

Safety, Efficacy, and Preventive Role of Subcutaneous and Sublingual Allergen Immunotherapy for the Treatment of Pediatric Asthma.

Arianna Giannetti, Giampaolo Ricci, Michela Procaccianti, Angelica Santoro, Carlo Caffarelli

Open access · goldAbstract readReview
In one paragraph

Review in Journal of asthma and allergy, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.0field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 13 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Review
  6. Safety of allergen-specific immunotherapy in children.Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology · 2022
    Article
  7. Review
  8. [Retrospective Study of Mite-Specific Subcutaneous Immunotherapy in Children].Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition · 2021
    Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Arianna GiannettiPediatric Unit, Department of Medical and Surgical Sciences, University of Bologna, Bologna, Italy.
Giampaolo RicciPediatric Unit, Department of Medical and Surgical Sciences, University of Bologna, Bologna, Italy.ORCID 0000-0002-3660-8750
Michela ProcacciantiClinica Pediatrica, Department of Medicine and Surgery, University of Parma, Parma, Italy.
Angelica SantoroClinica Pediatrica, Department of Medicine and Surgery, University of Parma, Parma, Italy.
Carlo CaffarelliClinica Pediatrica, Department of Medicine and Surgery, University of Parma, Parma, Italy.ORCID 0000-0001-7710-6995
University of Parma · ITUniversity of Bologna · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Allergen-specific immunotherapy is currently the only treatment with the potential to modify and prevent progression of allergic asthma in children. In clinical practice, it is available in two forms: subcutaneous immunotherapy and sublingual immunotherapy. Trials and meta-analyses showed both the safety and the short- and long-term benefits of allergen-specific immunotherapy in asthmatic children. However, its use and role in asthma remains controversial, since studies are largely heterogeneous. This is mainly due to the lack of consensus on the optimal primary outcome to be considered for clinical trials evaluating the efficacy of allergen-specific immunotherapy in asthma. Therefore, well-conducted researchis needed using standardized and validated tools to evaluate key outcomes in asthmatic children.

Indexed as

allergen-specific immunotherapyallergyasthmachildrengrasshouse dust mite

Identifiers

PMID33204114
PMCPMC7667503
OpenAlexW3100574446

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.