Evidence map›Paper›PMID 33204073›Full record

ArticlePatient preference and adherence2020

Patient Treatment Preferences for Heart Failure Medications: A Mixed Methods Study.

Katy E Trinkley, Michael G Kahn, Larry A Allen, Heather Haugen, Miranda E Kroehl, Chen-Tan Lin, Daniel C Malone, Daniel D Matlock

Abstract read
In one paragraph

Article in Patient preference and adherence, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Advancing Guideline-Directed Medical Therapy in Heart Failure: Overcoming Challenges and Maximizing Benefits.American journal of cardiovascular drugs : drugs, devices, and other interventions · 2024
    Review
  5. Review
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Katy E TrinkleyDepartment of Clinical Pharmacy, University of Colorado Skaggs School of Pharmacy and Pharmaceutical Sciences, Aurora, CO, USA.ORCID 0000-0003-2041-7404
Michael G KahnSection of Informatics and Data Science, Department of Pediatrics, University of Colorado School of Medicine, Aurora, CO, USA.ORCID 0000-0003-4786-6875
Larry A AllenDepartment of Medicine, University of Colorado School of Medicine, Aurora, CO, USA.ORCID 0000-0003-2540-3095
Heather HaugenUniversity of Colorado, Colorado Clinical and Translational Sciences Institute (CCTSI), Aurora, CO, USA.
Miranda E KroehlCharter Communications Corporation, Greenwood Village, CO, USA.
Chen-Tan LinDepartment of Medicine, University of Colorado School of Medicine, Aurora, CO, USA.ORCID 0000-0002-8678-7945
Daniel C MaloneDepartment of Pharmacotherapy, University of Utah Skaggs College of Pharmacy, Salt Lake City, UT, USA.
Daniel D MatlockDepartment of Medicine, University of Colorado School of Medicine, Aurora, CO, USA.ORCID 0000-0001-9597-9642

Funding

IMPlementation to Achieve Clinical Transformation (IMPACT): The Colorado Training ProgramK12HL137862 · NHLBI · UNIVERSITY OF COLORADO DENVER · PI GLASGOW, RUSSELL E, HAVRANEK, EDWARD PAUL · 2017 to 2021
$2.9M
NHLBI NIH HHS K12 HL137862
6 · The paper itself

Abstract

introductionConsideration of patient preferences for guideline-directed medical therapies (GDMT) for heart failure with reduced ejection fraction (HFrEF) may help improve major gaps in prescribing and adherence. This study aimed to identify the range and relative priority of factors influencing patients' decisions to take HFrEF medications. MATERIALS AND

methodsThis was a convergent mixed methods study of patients with HFrEF. Focus groups were conducted to identify a list of factors followed by individuals rating and ranking the influence of each factor on their decision to take a medication. Using thematic analysis, we summarized preferences into categories.

resultsTwo focus groups with 13 participants reported 22 factors. Of the factors, "keeping you alive" was most commonly ranked in the top three (seven participants), followed by "communication and understanding" (six participants). Factors were summarized into six categories (listed in order of patient-reported influence): 1) demonstrated improvements in quality of life and longevity, 2) decreased risk of hospitalization, 3) opportunity for shared decision-making and trust in provider, 4) absence of adverse events, 5) affordability, and 6) convenience of taking and absence of interference with daily life.

conclusionPatients prioritize treatment benefits and being informed more than risks, cost and inconvenience of taking HFrEF medications.

Indexed as

heart failuremedication preferencespatient preferencestreatment preferences

Identifiers

PMID33204073
PMCPMC7667168

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.