ArticleGenetics in medicine : official journal of the American College of Medical Genetics2021
Cardiovascular risk factors and body composition in adults with achondroplasia.
Article in Genetics in medicine : official journal of the American College of Medical Genetics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 11 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
11 citing papers in PubMed, 40 citations in OpenAlex.
- Body composition, anthropometry, and resting energy expenditure in adults with achondroplasia: a pilot study to determine best practices.Orphanet journal of rare diseases · 2025Article
- Considerations for Anthropometry Specific to People with Disproportionate Short Stature.Advances in therapy · 2025Review
- European Achondroplasia Forum Practical Considerations for Following Adults with Achondroplasia.Advances in therapy · 2024Article
- Article
- Higher rates of non-skeletal complications and greater healthcare needs in achondroplasia compared to the general UK population: a matched cohort study using the CPRD database.Orphanet journal of rare diseases · 2023Article
- Fat infiltration in the thigh muscles is associated with symptomatic spinal stenosis and reduced physical functioning in adults with achondroplasia.Orphanet journal of rare diseases · 2023Article
- What to Expect of Feeding Abilities and Nutritional Aspects in Achondroplasia Patients: A Narrative Review.Genes · 2023Review
- Optimising care and follow-up of adults with achondroplasia.Orphanet journal of rare diseases · 2022Article
- Optimising the diagnosis and referral of achondroplasia in Europe: European Achondroplasia Forum best practice recommendations.Orphanet journal of rare diseases · 2022Article
- International Consensus Statement on the diagnosis, multidisciplinary management and lifelong care of individuals with achondroplasia.Nature reviews. Endocrinology · 2022Review
- Advantages and Disadvantages of Different Treatment Methods in Achondroplasia: A Review.International journal of molecular sciences · 2021Review
Corrections and comments
- Erratum issued
Authors and funding
10 authors at 5 institutions in 3 countries.
Funding
Abstract
purposeAn increased cardiovascular mortality has been reported in achondroplasia. This population-based, case-control study investigated cardiovascular risk factors and body composition in Norwegian adults with achondroplasia.
methodsWe conducted anthropometric, clinical, and laboratory assessments in 49 participants with achondroplasia, of whom 40 completed magnetic resonance imaging (MRI) for body composition analysis. Controls consisted of 98 UK Biobank participants, matched for body mass index (BMI), sex, and age.
resultsParticipants were well matched for BMI (33.3 versus 32.5 kg/m
conclusionDespite a high BMI, the cardiovascular risks appeared similar or lower in achondroplasia compared with controls, indicating that other factors might contribute to the increased mortality observed in this condition.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.