ArticleNature communications2020
Molecular variation in a functionally divergent homolog of FCA regulates flowering time in Arabidopsis thaliana.
Article in Nature communications, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
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Who cites it
20 citing papers in PubMed, 52 citations in OpenAlex.
- Constitutive overexpression of GRF21, a 14-3-3 family protein, delays flowering time in maize (Zea mays).BMC plant biology · 2026Article
- Understanding the role of GhRCC1.61 in flowering time in upland cotton through integrated analyses of gene family, RNA-seq, VIGS and allelic variation.Plant cell reports · 2025Article
- PcMYBs responded to 6-BA to regulate PcCKXs to promote germination of primary rhizome buds of Polygonatum cyrtonema Hua.BMC plant biology · 2025Article
- Glutathionylation-mediated degradation of a cap-binding protein enhances Arabidopsis resistance to Plutella xylostella.The Plant cell · 2025Article
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- DM_CorrMatch: a semi-supervised semantic segmentation framework for rapeseed flower coverage estimation using UAV imagery.Plant methods · 2025Article
- Cooperative condensation of RNA-DIRECTED DNA METHYLATION 16 splicing isoforms enhances heat tolerance in Arabidopsis.Nature communications · 2025Article
- Loss-of-function of LIGULELESS1 activates the jasmonate pathway and promotes maize resistance to corn leaf aphids.Plant biotechnology journal · 2024Article
- The plant terpenes DMNT and TMTT function as signaling compounds that attract Asian corn borer (Ostrinia furnacalis) to maize plants.Journal of integrative plant biology · 2024Article
- SISTER OF FCA physically associates with SKB1 to regulate flowering time in Arabidopsis thaliana.BMC plant biology · 2024Article
- Genome-wide association study reveals loci and candidate genes of flowering time in jute (Molecular breeding : new strategies in plant improvement · 2023Article
- Phase separation in flowering control: DCP5 and SSF co-regulate FLC by liquid-liquid phase separation.The Plant cell · 2023Article
- The P-body component DECAPPING5 and the floral repressor SISTER OF FCA regulate FLOWERING LOCUS C transcription in Arabidopsis.The Plant cell · 2023Article
- Genome-wide association study of 23 flowering phenology traits and 4 floral agronomic traits in tree peony (Horticulture research · 2023Article
- Transcriptome analysis of floral bud development and function analysis of a novel CO gene in Paeonia × lemoinei 'High Noon'.Scientific reports · 2022Article
- Identification of noble candidate gene associated with sensitivity to phytotoxicity of etofenprox in soybean.Scientific reports · 2022Article
- Genome and pan-genome assembly of asparagus bean (Frontiers in plant science · 2022Article
- Genome-Wide Association Analyses to Identify SNPs Related to Drought Tolerance.Methods in molecular biology (Clifton, N.J.) · 2022Article
- Expression GWAS ofFrontiers in plant science · 2021Article
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Authors and funding
11 authors at 2 institutions in 2 countries.
Funding
Abstract
The identification and functional characterization of natural variants in plants are essential for understanding phenotypic adaptation. Here we identify a molecular variation in At2g47310 that contributes to the natural variation in flowering time in Arabidopsis thaliana accessions. This gene, which we term SISTER of FCA (SSF), functions in an antagonistic manner to its close homolog FCA. Genome-wide association analysis screens two major haplotypes of SSF associated with the natural variation in FLC expression, and a single polymorphism, SSF-N414D, is identified as a main contributor. The SSF414N protein variant interacts more strongly with CUL1, a component of the E3 ubiquitination complex, than the SSF414D form, mediating differences in SSF protein degradation and FLC expression. FCA and SSF appear to have arisen through gene duplication after dicot-monocot divergence, with the SSF-N414D polymorphism emerging relatively recently within A. thaliana. This work provides a good example for deciphering the functional importance of natural polymorphisms in different organisms.
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