Evidence map›Paper›PMID 33203807›Full record

ArticleMolecules and cells2020

HIF-1α-Dependent Induction of Carboxypeptidase A4 and Carboxypeptidase E in Hypoxic Human Adipose-Derived Stem Cells.

Yunwon Moon, Ramhee Moon, Hyunsoo Roh, Soojeong Chang, Seongyeol Lee, Hyunsung Park

Abstract read
In one paragraph

Article in Molecules and cells, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Yunwon MoonDepartment of Life Science, University of Seoul, Seoul 02504, Korea.ORCID https://orcid.org/0000-0003-2878-2887
Ramhee MoonDepartment of Life Science, University of Seoul, Seoul 02504, Korea.ORCID https://orcid.org/0000-0001-6213-9962
Hyunsoo RohDepartment of Life Science, University of Seoul, Seoul 02504, Korea.ORCID https://orcid.org/0000-0003-4065-5186
Soojeong ChangDepartment of Life Science, University of Seoul, Seoul 02504, Korea.ORCID https://orcid.org/0000-0002-1961-6687
Seongyeol LeeDepartment of Life Science, University of Seoul, Seoul 02504, Korea.ORCID https://orcid.org/0000-0003-2086-9662
Hyunsung ParkDepartment of Life Science, University of Seoul, Seoul 02504, Korea.ORCID https://orcid.org/0000-0002-6890-428X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hypoxia induces the expression of several genes through the activation of a master transcription factor, hypoxia-inducible factor (HIF)-1α. This study shows that hypoxia strongly induced the expression of two carboxypeptidases (CP), CPA4 and CPE, in an HIF-1α-dependent manner. The hypoxic induction of

Indexed as

Carboxypeptidase HCarboxypeptidases ACell HypoxiaHumansHypoxia-Inducible Factor 1, alpha SubunitStem CellsCarboxypeptidase HCarboxypeptidases AHIF1A protein, humanHypoxia-Inducible Factor 1, alpha Subunitcarboxypeptidase A4carboxypeptidase Ehuman adipose-derived stem cellshypoxiahypoxia-inducible factor-1α

Identifiers

PMID33203807
PMCPMC7700838

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.