ArticlemBio2020
Staphylococcal DNA Repair Is Required for Infection.
Open access · goldAbstract read
In one paragraph
Article in mBio, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
0.5field-weighted citation impact, top 22% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
21 citing papers in PubMed, 31 citations in OpenAlex.
- Host-Pathogen Dual Targeting With Repurposed Drugs Identifies a Synergistic Therapy for Intracellular Staphylococcus aureus.MicrobiologyOpen · 2026Article
- Preclinical evaluation of repositioned non-antibiotic agents against Staphylococcus aureus: a network meta-analysis of survival outcomes.World journal of microbiology & biotechnology · 2025Article
- Glucose-induced active lysogeny of prophage ΦSa3XN promotes Staphylococcus aureus virulence.Virology journal · 2025Article
- Ultrahigh-throughput screening of heterogeneous vancomycin-intermediate Staphylococcus aureus based on fluorescence-activated droplet sorting.BMC medicine · 2025Article
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- Acquisition of daptomycin resistance in patients results in decreased virulence inInfection and immunity · 2025Article
- Integration of Transcriptomics and Proteomics to Elucidate Inhibitory Effect and Mechanism of Antifungalmycin B from MarineMarine drugs · 2025Article
- Strategies for Survival ofInternational journal of molecular sciences · 2025Review
- Integrated metagenomics and transcriptomics analysis reveals pathways associated with oral periapical lesions formation and progression.Current research in microbial sciences · 2025Article
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- Development of an inhibitor of the mutagenic SOS response that suppresses the evolution of quinolone antibiotic resistance.Chemical science · 2024Article
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- Antifungal Activity and Potential Action Mechanism of Allicin against Trichosporon asahii.Microbiology spectrum · 2023Article
- Prediction model of colorectal cancer (CRC) lymph node metastasis based on intestinal bacteria.Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2023Article
- Pathogenic bacteria experience pervasive RNA polymerase backtracking during infection.bioRxiv : the preprint server for biology · 2023Article
- XerC Is Required for the Repair of Antibiotic- and Immune-Mediated DNA Damage in Staphylococcus aureus.Antimicrobial agents and chemotherapy · 2023Article
- Essential Fitness Repertoire of Staphylococcus aureus during Co-infection with Acinetobacter baumanniimSystems · 2022Article
- Defects in DNA double-strand break repair resensitize antibiotic-resistant Escherichia coli to multiple bactericidal antibiotics.MicrobiologyOpen · 2022Article
- RexAB Promotes the Survival of Staphylococcus aureus Exposed to Multiple Classes of Antibiotics.Antimicrobial agents and chemotherapy · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors at 3 institutions in 2 countries.
Kam Pou HaMRC Centre for Molecular Bacteriology and Infection, Imperial College London, London, United Kingdom.
Rebecca S ClarkeMRC Centre for Molecular Bacteriology and Infection, Imperial College London, London, United Kingdom.ORCID 0000-0003-2342-7923
Gyu-Lee KimDepartment of Pathology, Immunology and Laboratory Medicine, Center for Immunity and Inflammation, Rutgers New Jersey Medical School, Newark, New Jersey, USA.
Jane L BrittanBristol Dental School, University of Bristol, Bristol, United Kingdom.
Jessica E RowleyMRC Centre for Molecular Bacteriology and Infection, Imperial College London, London, United Kingdom.
Despoina A I MavridouMRC Centre for Molecular Bacteriology and Infection, Imperial College London, London, United Kingdom.
Dane ParkerDepartment of Pathology, Immunology and Laboratory Medicine, Center for Immunity and Inflammation, Rutgers New Jersey Medical School, Newark, New Jersey, USA.
Thomas B ClarkeMRC Centre for Molecular Bacteriology and Infection, Imperial College London, London, United Kingdom.
Angela H NobbsBristol Dental School, University of Bristol, Bristol, United Kingdom.ORCID 0000-0003-3813-4410
Andrew M EdwardsMRC Centre for Molecular Bacteriology and Infection, Imperial College London, London, United Kingdom a.edwards@imperial.ac.uk.ORCID 0000-0002-7173-7355
Imperial College London · GBRutgers, The State University of New Jersey · USUniversity Of Bristol Dental Hospital · GB
Funding
ROLE OF TYPE III INTERFERONS IN STAPHYLOCOCCUS AUREUS RESPIRATORY TRACT INFECTIONR01HL134870 · NHLBI · RBHS-NEW JERSEY MEDICAL SCHOOL · PI PARKER, DANE · 2017 to 2020
$1.8MHumanized lung implant mouse model to study Staphylococcus aureus airway interactionsR21AI153646 · NIAID · RBHS-NEW JERSEY MEDICAL SCHOOL · PI PARKER, DANE · 2020 to 2021
$430kBritish Heart Foundation PG/17/10/32829Department of HealthMedical Research Council MR/J006874/1Medical Research Council MR/M009505/1NHLBI NIH HHS R01 HL134870NIAID NIH HHS HHSN272200700055CNIAID NIH HHS R21 AI153646
Abstract
To cause infection,
Indexed as
DNA RepairHost-Pathogen InteractionsAnimalsBacterial ProteinsDNA Breaks, Double-StrandedExodeoxyribonucleasesFemaleHumansMiceMice, Inbred C57BLNeutrophilsReactive Oxygen SpeciesRespiratory BurstStaphylococcal InfectionsStaphylococcus aureusAddAB enzymeBacterial ProteinsExodeoxyribonucleasesReactive Oxygen SpeciesDNA damageEnterococcusneutrophilsoxidative burstrespiratory burstSOS systemStaphylococcusStreptococcus
Identifiers
What OpenQuestion holds
Textmetadata
LicenceCC BY
Read underepoch 390
Registered trials
None linked
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.