ArticleJournal of orthopaedic surgery and research2020
Perioperative hypoalbuminemia is a risk factor for wound complications following posterior lumbar interbody fusion.
Article in Journal of orthopaedic surgery and research, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers, 1 of them a synthesis that pooled it.
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Who cites it
36 citing papers in PubMed, 1 synthesis or guideline pooled it, 61 citations in OpenAlex.
- Association between malnutrition and surgical site wound infection among spinal surgery patients: A meta-analysis.International wound journal · 2023Pooled it
- Associations of Preoperative and Early Postoperative Biomarkers with Wound Complications in a Clinically Restricted Surgical Population: A Retrospective Cohort Study.Journal of clinical medicine · 2026Article
- Clinical and Surgical Risk Factors for Wound Healing Disorders Following Non-Instrumented Lumbar Spine Surgery Using Penalized Regression Analysis.Journal of clinical medicine · 2026Article
- Risk factors for surgical site infections after spinal surgery: a systematic review and meta-analysis.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2026Review
- The impact of preoperative nutritional status on 30-day outcomes after elective lumbar laminectomy for lumbar stenosis: a population-based cohort analysis.Asian spine journal · 2026Article
- Risk Factors for Postoperative Complications in Different Fusion Surgical Approaches for Lumbar Degenerative Diseases.Journal of clinical medicine · 2026Article
- Prognostic nutritional index and long-term outcomes after coronary artery bypass grafting.BMC surgery · 2026Article
- From Serum to Surgery: The Significance of Albumin in Preoperative Risk Stratification-An Analysis of 200,015 Plastic Surgery Patients.Aesthetic plastic surgery · 2026Article
- Risk factors for persistent wound drainage after hemiarthroplasty in elderly hip fracture patients.Joint diseases and related surgery · 2026Article
- Environmental, Nutritional, and Therapeutic Factors That Affect Surgical Wound Healing: A Narrative Review of Experimental Findings From the Last 5 Years.Health science reports · 2026Article
- Distribution of pathogenic bacteria and analysis of risk factors for surgical site infections after hepatobiliary surgery.BMC infectious diseases · 2026Article
- Machine learning model for predicting malnutrition risk in lung cancer patients after thoracoscopic resection: a multi-center study.Frontiers in oncology · 2026Article
- Nutritional status and postoperative recovery outcomes in patients undergoing orthopedic surgery.Frontiers in nutrition · 2026Article
- Exploring the predictors of postoperative complications in hand surgery: a cross-sectional analysis.BMC surgery · 2025Article
- Serum Albumin Level as a Predictor of Failure to Rescue in Patients Undergoing Surgery for Spinal Metastases.Cancers · 2025Article
- Article
- The implications of preoperative hypoalbuminemia on postoperative readmission, reoperation, and mortality among orthopaedic trauma patients: A systematic review and meta-analysis.Journal of clinical orthopaedics and trauma · 2025Article
- Analysis of risk factors, pathogenic bacteria characteristics, and drug resistance of postoperative surgical site infection in adults with limb fractures.Chinese journal of traumatology = Zhonghua chuang shang za zhi · 2025Article
- Predictive Value of Preoperative Nutritional Risk Index for Screw Loosening After Lumbar Interbody Fusion in Elderly Patients With Lumbar Spine Diseases.Orthopaedic surgery · 2025Article
- Construction and validation of a nomogram predictive model for assessing the risk of surgical site infections following posterior lumbar fusion surgery.Scientific reports · 2025Article
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Authors and funding
6 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundAlthough serum albumin levels are increasingly used as an indicator of nutritional status in the clinic, the relationship between perioperative hypoalbuminemia and wound complications after posterior lumbar interbody fusion in the treatment of lumbar degenerative disease remains ambiguous. The aim of this study was to evaluate perioperative serum albumin in relation to postoperative wound complications after posterior lumbar interbody fusion in the treatment of single-segment lumbar degenerative disease. MATERIAL AND
methodsWe reviewed patients who underwent single-segment posterior lumbar interbody fusion surgery from December 2014 to April 2017 in the Department of Orthopedics at the First Affiliated Hospital of Chongqing Medical University. Perioperative (preoperative and early postoperative) serum albumin levels were assessed in all patients and were used to quantify nutritional status. We divided the patients into a surgical wound dehiscence (SWD) group and a normal wound healing group and into a surgical site infection (SSI) group and a non-SSI group. To evaluate the relationship between perioperative serum albumin level and postoperative wound complications, we conducted univariate and multiple logistic regression analyses.
resultsA total of 554 patients were enrolled in the study. The univariate and multiple logistic regression analysis of these differences showed that preoperative serum albumin < 3.5 g/dl (P = 0.001) and postoperative serum albumin < 3.0 g/dl (P = 0.001) were significantly correlated to SWD. There were also significant differences between the SSI groups in terms of preoperative serum albumin < 3.5 g/dl (P = 0.001) and chronic steroid use (P = 0.003). Additionally, the increased hospitalization costs (P < 0.001) and length of hospitalization (P < 0.001) were statistically significant for patients with perioperative hypoalbuminemia.
conclusionsFor patients who underwent single-segment posterior lumbar interbody fusion surgery, we need to pay more attention to perioperative hypoalbuminemia and chronic steroid use, which are more likely to be associated with increased wound complications, hospitalization costs, and length of hospitalization after surgery. Adequate assessment and management of these risk factors will help reduce wound complications and hospital stays for surgical patients and will save medical costs.
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