ArticleBMC nephrology2020
A prospective study on total protein, plant protein and animal protein in relation to the risk of incident chronic kidney disease.
Article in BMC nephrology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 3 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
23 citing papers in PubMed, 3 syntheses or guidelines pooled it, 53 citations in OpenAlex.
- Dietary intake of total, animal, and plant proteins and risk of chronic kidney disease: systematic review and dose-response meta-analysis of prospective cohort studies.BMC nutrition · 2025Pooled it
- Association between dietary protein intake and risk of chronic kidney disease: a systematic review and meta-analysis.Frontiers in nutrition · 2024Pooled it
- The Association between Total Protein, Animal Protein, and Animal Protein Sources with Risk of Inflammatory Bowel Diseases: A Systematic Review and Meta-Analysis of Cohort Studies.Advances in nutrition (Bethesda, Md.) · 2023Pooled it
- Trial
- Higher habitual protein intake is not linked to decline of iohexol-measured GFR in adults ≥40 years.Clinical kidney journal · 2026Article
- Vegetarian Dietary Patterns and Diet-Related Metabolites Are Associated With Kidney Function in the Adventist Health Study-2 Cohort.Journal of renal nutrition : the official journal of the Council on Renal Nutrition of the National Kidney Foundation · 2026Article
- Gut microbiota-liver-kidney axis in diabetic kidney disease: mechanistic insights into amino acid metabolism and nutritional intervention strategies targeting natural bioactive compounds.Frontiers in nutrition · 2026Review
- Nutrition across the Entire Lifespan in CKD: From Childhood to Senescence.Clinical journal of the American Society of Nephrology : CJASN · 2025Article
- The Effect of Protein Intake on Bone Disease, Kidney Disease, and Sarcopenia: A Systematic Review.Current developments in nutrition · 2025Review
- Differential effects of plant protein ratio on renal function and mortality across CKD stages.Frontiers in nutrition · 2025Article
- Compliance with a Healthful Plant-Based Diet Is Associated with Kidney Function in Patients with Autosomal Dominant Polycystic Kidney Disease.Nutrients · 2024Article
- Research Progress on New Functions of Animal and Plant Proteins.Foods (Basel, Switzerland) · 2024Review
- What is central to renal nutrition: protein or sodium intake?Clinical kidney journal · 2023Review
- Differences in prevalence and management of chronic kidney disease among T2DM inpatients at the grassroots in Beijing and Taiyuan: a retrospective study.Journal of health, population, and nutrition · 2023 · on this mapArticle
- Metabolomics of Dietary Intake of Total, Animal, and Plant Protein: Results from the Atherosclerosis Risk in Communities (ARIC) Study.Current developments in nutrition · 2023Article
- Vegan Diet Is Associated with a Lower Risk of Chronic Kidney Disease in Patients with Hyperuricemia.Nutrients · 2023Article
- The association between plant and animal protein intake and quality of life in patients undergoing hemodialysis.Frontiers in nutrition · 2023Article
- Total protein intake and subsequent risk of chronic kidney disease: the Circulatory Risk in Communities Study.Environmental health and preventive medicine · 2023Article
- Low-protein diet is inversely related to the incidence of chronic kidney disease in middle-aged and older adults: results from a community-based prospective cohort study.European journal of nutrition · 2022Article
- Dietary protein score and carbohydrate quality index with the risk of chronic kidney disease: Findings from a prospective cohort study.Frontiers in nutrition · 2022Article
Corrections and comments
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Authors and funding
5 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe link between dietary protein intake and the risk of kidney dysfunction is always a challenging issue. This study aimed to investigate the relationship between total protein, plant protein, and animal protein intake with the risk of incident chronic kidney disease (CKD).
methodsThis study was performed on 1639 adults aged ≥27 years who participated in the Tehran Lipid and Glucose Study. Dietary data were evaluated using a valid and reliable semi-quantitative food frequency questionnaire (FFQ). Total protein content, plant protein, and animal protein of each participant were calculated. Glomerular filtration rate (GFR) less than 60 mL / min / 1.73 m
resultsAfter adjusting for age, sex, body mass index, smoking, total energy intake, total fiber intake, dietary fat, physical activity, diabetes, and hypertension, there was no significant association of total protein and animal protein consumptions with the incidence of CKD. After adjustment for confounders, compared with the lowest tertile of plant protein consumption, OR of incident CKD in the highest tertile was 0.29 (95% confidence interval [95% CI] 0.15 to 0.55) with a significant trend (P for trend < 0.001).
conclusionThe results of this study confirmed an inverse association between plant protein intake and the risk of incident CKD, which demonstrates the protective role of plant-based protein in a diet on kidney function.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.