Evidence map›Paper›PMID 33203318›Full record

ReviewJournal of dental research2021

Key Elements of Gingival Epithelial Homeostasis upon Bacterial Interaction.

J S Lee, Ö Yilmaz

Open access · greenAbstract readReview
In one paragraph

Review in Journal of dental research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
1.5field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 22 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Review
  5. Article
  6. Article
  7. Article
  8. Review
  9. Article
  10. Article
  11. Article
  12. [Research Updates: Relationship between Gingival Epithelial Intercellular Junctions and Periodontal Pathogenic Bacteria].Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition · 2022
    Review
  13. The Regulatory Effect of Coaggregation BetweenFrontiers in cellular and infection microbiology · 2022
    Article
  14. Article
  15. Article
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

J S LeeDepartment of Oral Health Sciences, College of Dental Medicine, Medical University of South Carolina, Charleston, SC, USA.ORCID 0000-0001-6937-9416
Ö YilmazDepartment of Oral Health Sciences, College of Dental Medicine, Medical University of South Carolina, Charleston, SC, USA.ORCID 0000-0003-3487-7217
Medical University of South Carolina · US

Funding

T-COHR: Training in Craniofacial and Oral Health ResearchT32DE017551 · NIDCR · MEDICAL UNIVERSITY OF SOUTH CAROLINA · PI YAO, HAI · 2006 to 2025
$10.3M
Modulation of epithelial cell response by P. gingivalisR01DE016593 · NIDCR · UNIVERSITY OF FLORIDA · PI YILMAZ, OZLEM · 2006 to 2016
$3.3M
Turning on Persistence: Novel Molecular Determinants that Underpin P. gingivalis' Intracellular Survival In Epithelial CellsR01DE030313 · NIDCR · MEDICAL UNIVERSITY OF SOUTH CAROLINA · PI YILMAZ, OZLEM · 2020 to 2024
$2.3M
Modulation of Epithelial Cell Response by P. gingivalisR56DE016593 · NIDCR · MEDICAL UNIVERSITY OF SOUTH CAROLINA · PI YILMAZ, OZLEM · 2019 to 2019
$355k
The role of surface-bound ectonucleotidase CD73 in modulation of Porphyromonas gingivalis infection in gingival epithelial cellsF30DE029103 · NIDCR · MEDICAL UNIVERSITY OF SOUTH CAROLINA · PI LEE, JADEN SOPHIEN · 2019 to 2021
$151k
NIDCR NIH HHS F30 DE029103NIDCR NIH HHS R01 DE016593NIDCR NIH HHS R01 DE030313NIDCR NIH HHS R56 DE016593NIDCR NIH HHS T32 DE017551
6 · The paper itself

Abstract

Epithelia are structurally integral elements in the fabric of oral mucosa with significant functional roles. Similarly, the gingival epithelium performs uniquely critical tasks in responding to a variety of external stimuli and dangers through the regulation of specific built-in molecular mechanisms in a context-dependent fashion at cellular levels. Gingival epithelial cells form an anatomic architecture that confers defense, robustness, and adaptation toward external aggressions, most critically to colonizing microorganisms, among other functions. Accordingly, recent studies unraveled previously uncharacterized response mechanisms in gingival epithelial cells that are constructed to rapidly exert biocidal effects against invader pathobiotic bacteria, such as

Indexed as

GingivaPorphyromonas gingivalisEpithelial CellsHomeostasisMouth Mucosachronic infectiondanger signalingepithelial defense mechanismsepithelial homeostasisgingival epitheliaopportunistic bacteria

Identifiers

PMID33203318
PMCPMC7989138
OpenAlexW3099873113

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.