Observational studyThe Journal of international medical research2020
Changes in perioperative hemoglobin and hematocrit in patients undergoing total knee arthroplasty: a prospective observational study of optimal timing of measurement.
Observational study in The Journal of international medical research, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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Who cites it
7 citing papers in PubMed.
- Efficacy and Safety of Bone Wax Application at Different Time Points to Reduce Postoperative Blood Loss in Total Knee Arthroplasty: A Prospective Randomized Controlled Trial.Orthopaedic surgery · 2024Trial
- Effect of a Topical Thrombin-Carboxymethyl Starch Hemostatic Agent on Perioperative Hemoglobin Course: A Propensity Score-Matched Study.Medicina (Kaunas, Lithuania) · 2026Observational
- Article
- Calculated Versus Estimated Blood Loss in Plastic Breast Surgery.Plastic and reconstructive surgery. Global open · 2025Article
- Clinical Efficacy of Endoscopy-Assisted Anterior Cervical Discectomy and Fusion for Single-Segment Cervical Spondylotic Myelopathy: A Retrospective, Propensity Score-Matched Study.Therapeutics and clinical risk management · 2025Article
- Are Risk Factors for Postoperative Significant Hemorrhage following Total Knee Arthroplasty Potentially Modifiable? A Retrospective Cohort Study.Journal of personalized medicine · 2022Article
- Comparing the Efficacy of Articulating Spacers in Two-Stage Revision for Periprosthetic Joint Infection Following Total Knee Arthroplasty: All-Cement Spacers vs Sterilized Replanted Metal-Polyethylene Spacers.International journal of general medicine · 2022Article
Corrections and comments
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveThis study was performed to depict the patterns of change in the perioperative hemoglobin (Hb) concentration and hematocrit (Hct) and to identify the optimal timing of Hb and Hct measurement in patients undergoing total knee arthroplasty (TKA).
methodsThis prospective observational study involved 302 consecutive patients who underwent TKA. The patients were kept in hospital for 1 full week postoperatively. Hb and Hct measurements were performed preoperatively and on days 1 to 7 postoperatively and then during clinic visits at 1, 3, and 6 months postoperatively.
resultsThe Hb concentration and Hct decreased during the first few days postoperatively and reached a nadir on postoperative day 4 and 3, respectively; they then recovered in the following days. Significant differences in the Hb concentration and Hct were detected between the preoperative period and day 1, between days 1 and 2, between days 2 and 3, between day 7 and 1 month, and between 1 and 3 months. A significant difference in the Hct was also detected between 3 and 6 months.
conclusionThe optimal timing of Hb and Hct measurement is on postoperative day 3 or 4. This timing accurately reflects ongoing hidden blood loss to better guide blood transfusions.
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