Evidence map›Paper›PMID 33203255›Full record

ArticleGlobal spine journal2022

Applied Machine Learning for Spine Surgeons: Predicting Outcome for Patients Undergoing Treatment for Lumbar Disc Herniation Using PRO Data.

Casper Friis Pedersen, Mikkel Østerheden Andersen, Leah Yacat Carreon, Søren Eiskjær

Abstract read
In one paragraph

Article in Global spine journal, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. A systematic review of minimum important changes for generic multi-attribute utility instruments and recommendations for their estimation.The European journal of health economics : HEPAC : health economics in prevention and care · 2025
    Pooled it
  2. Values derived from patient reported outcomes in spine surgery: a systematic review of the minimal clinically important difference, substantial clinical benefit, and patient acceptable symptom state.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2023
    Pooled it
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  7. Machine learning can predict surgical indication: new clustering model from a large adult spine deformity database.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2025
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  19. Predictive value of texture analysis on lumbar MRI in patients with chronic low back pain.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2023
    Observational
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Casper Friis Pedersen298597Lillebaelt Hospital, Middelfart, Denmark.ORCID https://orcid.org/0000-0002-1426-4096
Mikkel Østerheden Andersen298597Lillebaelt Hospital, Middelfart, Denmark.ORCID https://orcid.org/0000-0001-8478-8218
Leah Yacat Carreon298597Lillebaelt Hospital, Middelfart, Denmark.ORCID https://orcid.org/0000-0002-7685-9036
Søren EiskjærAalborg University, Denmark.ORCID https://orcid.org/0000-0002-6673-0116

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

STUDY

designRetrospective/prospective study.

objectiveModels based on preoperative factors can predict patients' outcome at 1-year follow-up. This study measures the performance of several machine learning (ML) models and compares the results with conventional methods.

methodsInclusion criteria were patients who had lumbar disc herniation (LDH) surgery, identified in the Danish national registry for spine surgery. Initial training of models included 16 independent variables, including demographics and presurgical patient-reported measures. Patients were grouped by reaching minimal clinically important difference or not for EuroQol, Oswestry Disability Index, Visual Analog Scale (VAS) Leg, and VAS Back and by their ability to return to work at 1 year follow-up. Data were randomly split into training, validation, and test sets by 50%/35%/15%. Deep learning, decision trees, random forest, boosted trees, and support vector machines model were trained, and for comparison, multivariate adaptive regression splines (MARS) and logistic regression models were used. Model fit was evaluated by inspecting area under the curve curves and performance during validation.

resultsSeven models were arrived at. Classification errors were within ±1% to 4% SD across validation folds. ML did not yield superior performance compared with conventional models. MARS and deep learning performed consistently well. Discrepancy was greatest among VAS Leg models.

conclusionsFive predictive ML and 2 conventional models were developed, predicting improvement for LDH patients at the 1-year follow-up. We demonstrate that it is possible to build an ensemble of models with little effort as a starting point for further model optimization and selection.

Indexed as

artificial intelligencedeep learninglumbar disc herniationmachine learningneural networkpatient-reported outcomespredictivePRO

Identifiers

PMID33203255
PMCPMC9344505

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.