Evidence map›Paper›PMID 33203120›Full record

ArticleInternational journal of molecular sciences2020

Injectable Gel Form of a Decellularized Bladder Induces Adipose-Derived Stem Cell Differentiation into Smooth Muscle Cells In Vitro.

Victoria Moreno-Manzano, Daria Zaytseva-Zotova, Eric López-Mocholí, Álvaro Briz-Redón, Berit Løkensgard Strand, Ángel Serrano-Aroca

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
3.9field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 33 citations in OpenAlex.

  1. Review
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  4. [Biological function of bladder smooth muscle cells regulated by multi-modal biomimetic stress].Sheng wu yi xue gong cheng xue za zhi = Journal of biomedical engineering = Shengwu yixue gongchengxue zazhi · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 2 countries.

Victoria Moreno-ManzanoNeuronal and Tissue Regeneration Lab, Centro de Investigación Príncipe Felipe, c/Eduardo Primo Yúfera, 3, 46012 Valencia, Spain.ORCID 0000-0002-6035-9491
Daria Zaytseva-ZotovaNOBIPOL, Department of Biotechnology and Food Science, NTNU Norwegian University of Science and Technology, Sem Sælands vei 6-8, N-7491 Trondheim, Norway.
Eric López-MocholíNeuronal and Tissue Regeneration Lab, Centro de Investigación Príncipe Felipe, c/Eduardo Primo Yúfera, 3, 46012 Valencia, Spain.
Álvaro Briz-RedónStatistics Office, City Council of Valencia, Plaza Ayuntamiento 1, 46002 Valencia, Spain.ORCID 0000-0001-7976-3534
Berit Løkensgard StrandNOBIPOL, Department of Biotechnology and Food Science, NTNU Norwegian University of Science and Technology, Sem Sælands vei 6-8, N-7491 Trondheim, Norway.
Ángel Serrano-ArocaBiomaterials and Bioengineering Lab, Centro de Investigación Traslacional San Alberto Magno, Universidad Católica de Valencia San Vicente Mártir, c/Guillem de Castro 94, 46001 Valencia, Spain.ORCID 0000-0002-9953-3848
Centro de Investigacion Principe Felipe · ESNorwegian University of Science and Technology · NOAyuntamiento de Valencia · ESValencia Catholic University Saint Vincent Martyr · ES

Funding

Conselleria de Cultura, Educación y Ciencia, Generalitat Valenciana AEI "RTI2018-095872-B-C21/ERDF"Fundación Universidad Católica de Valencia San Vicente Mártir 2019-231-003UCV and 2020-231-001UCV
6 · The paper itself

Abstract

Biologic scaffolds composed of extracellular matrix components have been proposed to repair and reconstruct a variety of tissues in clinical and pre-clinical studies. Injectable gels can fill and conform any three-dimensional shape and can be delivered to sites of interest by minimally invasive techniques. In this study, a biological gel was produced from a decellularized porcine urinary bladder by enzymatic digestion with pepsin. The enzymatic digestion was confirmed by visual inspection after dissolution in phosphate-buffered saline solution and Fourier-transform infrared spectroscopy. The rheological and biological properties of the gel were characterized and compared to those of the Matrigel

Indexed as

Cell DifferentiationAdipose TissueAnimalsFemaleHumansHydrogelsMyocytes, Smooth MuscleRabbitsStem CellsSwineTissue EngineeringUrinary BladderHydrogelsadipose-derived stem cellscell differentiationextracellular matrixgelMatrigelpepsinrheologyscaffoldsmooth muscle cellsviscoelasticity

Identifiers

PMID33203120
PMCPMC7696281
OpenAlexW3097979384

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.