ArticleSensors (Basel, Switzerland)2020
Closed-Loop Temperature Control Based on Fiber Bragg Grating Sensors for Laser Ablation of Hepatic Tissue.
Article in Sensors (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
19 citing papers in PubMed, 52 citations in OpenAlex.
- Automated Optical Treatment Based on Diffuse Reflectance Signals.Journal of biophotonics · 2026Article
- Verification and Validation of an Autotuning Proportional-Integral-Derivative Controller for Spatially Confined Magnetic Particle Hyperthermia.Journal of medical devices · 2026Article
- A review on radiofrequency, laser, and microwave ablations and their thermal monitoring through fiber Bragg gratings.iScience · 2023Review
- Towards phase-sensitive optical coherence tomography in smart laser osteotomy: temperature feedback.Lasers in medical science · 2023Article
- Measurement of Thermal Conductivity and Thermal Diffusivity of Porcine and Bovine Kidney Tissues at Supraphysiological Temperatures up to 93 °C.Sensors (Basel, Switzerland) · 2023Article
- Temperature Dependence of Thermal Properties of Ex Vivo Porcine Heart and Lung in Hyperthermia and Ablative Temperature Ranges.Annals of biomedical engineering · 2023Article
- Real-time automatic temperature regulation during in vivo MRI-guided laser-induced thermotherapy (MR-LITT).Scientific reports · 2023Article
- Validation of a Temperature-Feedback Controlled Automated Magnetic Hyperthermia Therapy Device.Cancers · 2023Article
- Design of a temperature-feedback controlled automated magnetic hyperthermia therapy device.Frontiers in thermal engineering · 2023Article
- Current Challenges in Image-Guided Magnetic Hyperthermia Therapy for Liver Cancer.Nanomaterials (Basel, Switzerland) · 2022Review
- Fiber-Optic Distributed Sensing Network for Thermal Mapping of Gold Nanoparticles-Mediated Radiofrequency Ablation.Biosensors · 2022Article
- Experimental Evaluation of Radiation Response and Thermal Properties of NPs-Loaded Tissues-Mimicking Phantoms.Nanomaterials (Basel, Switzerland) · 2022Article
- Recent Advances in Biomedical Photonic Sensors: A Focus on Optical-Fibre-Based Sensing.Sensors (Basel, Switzerland) · 2021Review
- Temperature Monitoring in Hyperthermia Treatments of Bone Tumors: State-of-the-Art and Future Challenges.Sensors (Basel, Switzerland) · 2021Review
- Fiber optic probe with functional polymer composites for hyperthermia.Biomedical optics express · 2021Article
- Concept of an In-Plane Displacement Sensor Based on Grating Interferometry with a Stepwise Change of Sensitivity.Sensors (Basel, Switzerland) · 2021Article
- Measurement of Ex Vivo Liver, Brain and Pancreas Thermal Properties as Function of Temperature.Sensors (Basel, Switzerland) · 2021Article
- Quasi-distributed fiber optic sensor-based control system for interstitial laser ablation of tissue: theoretical and experimental investigations.Biomedical optics express · 2021Article
- Hyperspectral Imagery for Assessing Laser-Induced Thermal State Change in Liver.Sensors (Basel, Switzerland) · 2021Article
Corrections and comments
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Authors and funding
7 authors at 2 institutions in 2 countries.
Funding
Abstract
Laser ablation (LA) of cancer is a minimally invasive technique based on targeted heat release. Controlling tissue temperature during LA is crucial to achieve the desired therapeutic effect in the organs while preserving the healthy tissue around. Here, we report the design and implementation of a real-time monitoring system performing closed-loop temperature control, based on fiber Bragg grating (FBG) spatial measurements. Highly dense FBG arrays (1.19 mm length, 0.01 mm edge-to-edge distance) were inscribed in polyimide-coated fibers using the femtosecond point-by-point writing technology to obtain the spatial resolution needed for accurate reconstruction of high-gradient temperature profiles during LA. The zone control strategy was implemented such that the temperature in the laser-irradiated area was maintained at specific set values (43 and 55 °C), in correspondence to specific radii (2 and 6 mm) of the targeted zone. The developed control system was assessed in terms of measured temperature maps during an ex vivo liver LA. Results suggest that the temperature-feedback system provides several advantages, including controlling the margins of the ablated zone and keeping the maximum temperature below the critical values. Our strategy and resulting analysis go beyond the state-of-the-art LA regulation techniques, encouraging further investigation in the identification of the optimal control-loop.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.