Evidence map›Paper›PMID 33203037›Full record

ArticleNutrients2020

Low-dose Bisphenol-A Promotes Epigenetic Changes at

Michele Longo, Federica Zatterale, Jamal Naderi, Cecilia Nigro, Francesco Oriente, Pietro Formisano, Claudia Miele, Francesco Beguinot

Open access · goldAbstract read
In one paragraph

Article in Nutrients, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
1.9field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 41 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Endocrine disruptors, obesity, and metabolic syndrome.Turkish journal of medical sciences · 2025
    Review
  6. Review
  7. Article
  8. Review
  9. Review
  10. Review
  11. Article
  12. Review
  13. Article
  14. Inherited Epigenetic Hallmarks of Childhood Obesity Derived from Prenatal Exposure to Obesogens.International journal of environmental research and public health · 2023
    Review
  15. Article
  16. Additives in Children's Nutrition-A Review of Current Events.International journal of environmental research and public health · 2022
    Review
  17. Article
  18. Review
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Michele LongoURT Genomics of Diabetes, Institute of Experimental Endocrinology and Oncology, National Research Council, 80131 Naples, Italy.ORCID 0000-0003-4798-0504
Federica ZatteraleURT Genomics of Diabetes, Institute of Experimental Endocrinology and Oncology, National Research Council, 80131 Naples, Italy.ORCID 0000-0002-1653-8652
Jamal NaderiURT Genomics of Diabetes, Institute of Experimental Endocrinology and Oncology, National Research Council, 80131 Naples, Italy.
Cecilia NigroURT Genomics of Diabetes, Institute of Experimental Endocrinology and Oncology, National Research Council, 80131 Naples, Italy.
Francesco OrienteURT Genomics of Diabetes, Institute of Experimental Endocrinology and Oncology, National Research Council, 80131 Naples, Italy.
Pietro FormisanoURT Genomics of Diabetes, Institute of Experimental Endocrinology and Oncology, National Research Council, 80131 Naples, Italy.ORCID 0000-0001-7020-6870
Claudia MieleURT Genomics of Diabetes, Institute of Experimental Endocrinology and Oncology, National Research Council, 80131 Naples, Italy.
Francesco BeguinotURT Genomics of Diabetes, Institute of Experimental Endocrinology and Oncology, National Research Council, 80131 Naples, Italy.
Institute for Experimental Endocrinology and Oncology · IT

Funding

European Foundation for the Study of Diabetes European Foundation for the Study of Diabetes (EFSD)/Boehringer Ingelheim (2018-2020)Ministero dell'Istruzione, dell'Università e della Ricerca PRIN 2017 and PON "RICERCA E INNOVAZIONE" 2014-2020 E FSC-progetto "Innovative Devices For SHAping the RIsk of Diabetes" (IDF SHARID)-ARS01_01270Regione Campania POR FESR 2014-2020-Obiettivo specifico 1.2.-Manifestazione di Interesse per la Realizzazione di Technology Platform nell'ambito della Lotta alle Patologie Oncologiche"-Projects COEPICA, RARE PLAT NET and SATIN
6 · The paper itself

Abstract

Exposure to endocrine-disrupting chemicals such as Bisphenol-A (BPA) is associated with an increase in obesity prevalence. Diet is the primary cause of human exposure to this contaminant. BPA promotes obesity by inducing adipocyte dysfunction and altering adipogenesis. Contradictory evidence and unanswered questions are reported in the literature concerning the BPA effects on adipogenesis. To clarify this issue, we tested the effects of prolonged low-dose BPA exposure on different phases of adipogenesis in committed

Indexed as

Promoter Regions, Genetic3T3-L1 CellsAdipocytesAdipogenesisAdipose TissueAnimalsBenzhydryl CompoundsBisphenol A CompoundsCell DifferentiationEndocrine DisruptorsEnvironmental PollutantsEpigenesis, GeneticFood ContaminationGene ExpressionInflammationInsulin ResistanceBenzhydryl Compoundsbisphenol ABisphenol A CompoundsEndocrine DisruptorsEnvironmental PollutantsPhenolsPPAR gammaadipogenesisadipose tissueadipose tissue dysfunctionBisphenol-Adiabetesenvironmental pollutantfood contaminantinflammationinsulin resistanceobesity

Identifiers

PMID33203037
PMCPMC7696502
OpenAlexW3099940335

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.