ArticlePolymers2020
Bacterial Nanocellulose-Enhanced Alginate Double-Network Hydrogels Cross-Linked with Six Metal Cations for Antibacterial Wound Dressing.
Article in Polymers, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
25 citing papers in PubMed, 72 citations in OpenAlex.
- Preparation and characterization of self-healing nanocomposite hydrogels based on chitosan/polyethylene glycol/bacterial nanocellulose for wound dressing applications.Scientific reports · 2026Article
- A modified bacterial nanocellulose-based advanced therapy product accelerates third-degree burn healing in murine models.NPJ Regenerative medicine · 2026Article
- Smart Wound Dressings and the Biological Parameters They Monitor: A Scoping Review.International wound journal · 2026Article
- Advances in Cellulose-Based Hydrogels for Drug Delivery: Preparation, Modification and Challenges.Gels (Basel, Switzerland) · 2025Review
- In Vitro Biodegradation and Biocompatibility of Bacterial Nanocellulose-Chitosan-Based Hydrogel Scaffolds for Bone Tissue Engineering.ACS omega · 2025Article
- Innovative Wound Healing Strategy Through Amorphization of Active Pharmaceutical Ingredients as an Effective Approach for Hydrogel Formulation.Pharmaceuticals (Basel, Switzerland) · 2025Review
- Article
- Advances in Hydrogel-Integrated SERS Platforms: Innovations, Applications, Challenges, and Future Prospects in Food Safety Detection.Biosensors · 2025Review
- Multifunctional tri-layer wound dressing containing ZNO nanoparticles and IGF-1 as an efficient biomaterial for healing of full thickness skin injuries.Asian journal of pharmaceutical sciences · 2025Article
- Current Paradigms and Future Challenges in Harnessing Nanocellulose for Advanced Applications in Tissue Engineering: A Critical State-of-the-Art Review for Biomedicine.International journal of molecular sciences · 2025Review
- Progress in Research on Metal Ion Crosslinking Alginate-Based Gels.Gels (Basel, Switzerland) · 2024Review
- Development of Mupirocin-Impregnated Bacterial Cellulosic Transdermal Patches for the Management of Skin Infection.ACS omega · 2024Article
- Copper incorporated biomaterial-based technologies for multifunctional wound repair.Theranostics · 2024Review
- Implications of pH and Ionic Environment in Chronic Diabetic Wounds: An Overlooked Perspective.Clinical, cosmetic and investigational dermatology · 2024Review
- Angiogenesis, hemocompatibility and bactericidal effect of bioactive natural polymer-based bilayer adhesive skin substitute for infected burned wound healing.Bioactive materials · 2023Article
- Consequences of Disturbing Manganese Homeostasis.International journal of molecular sciences · 2023Review
- Insight into the Latest Medical Applications of Nanocellulose.Materials (Basel, Switzerland) · 2023Review
- Bacterial Cellulose-Based Materials as Dressings for Wound Healing.Pharmaceutics · 2023Review
- A Comprehensive Review on Bio-Based Materials for Chronic Diabetic Wounds.Molecules (Basel, Switzerland) · 2023Review
- Modeling the Additive Effects of Nanoparticles and Polymers on Hydrogel Mechanical Properties Using Multifactor Analysis.Nanomaterials (Basel, Switzerland) · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 3 institutions in 3 countries.
Funding
Abstract
Alginate (Alg) and bacterial nanocellulose (BNC) have exhibited great potential in biomedical applications, especially wound dressing. Non-toxicity and a moisture-maintaining nature are common features making them favorable for functional dressing fabrication. BNC is a natural biopolymer that promotes major advances to the current and future biomedical materials, especially in a flat or tubular membrane form with excellent mechanical strength at hydrated state. The main drawback limiting wide applications of both BNC and Alg is the lack of antibacterial activity, furthermore, the inherent poor mechanical property of Alg leads to the requirement of a secondary dressing in clinical treatment. To fabricate composite dressings with antibacterial activity and better mechanical properties, sodium alginate was efficiently incorporated into the BNC matrix using a time-saving vacuum suction method followed by cross-linking through immersion in separate solutions of six cations (manganese, cobalt, copper, zinc, silver, and cerium). The results showed the fabricated composites had not only pH-responsive antibacterial activities but also improved mechanical properties, which are capable of acting as smart dressings. All composites showed non-toxicity toward fibroblast cells. Rat model evaluation showed the skin wounds covered by the dressings healed faster than by BNC.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.