Evidence map›Paper›PMID 33202922›Full record

ArticleBiosensors2020

Electrochemical Immunosensors Based on Screen-Printed Gold and Glassy Carbon Electrodes: Comparison of Performance for Respiratory Syncytial Virus Detection.

Wioleta Białobrzeska, Daniel Firganek, Maciej Czerkies, Tomasz Lipniacki, Marta Skwarecka, Karolina Dziąbowska, Zofia Cebula, Natalia Malinowska, Daniel Bigus, Ewelina Bięga and 4 more

Open access · goldAbstract read
In one paragraph

Article in Biosensors, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
2.5field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 31 citations in OpenAlex.

  1. Article
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  9. Review
  10. Pathogen detection with electrochemical biosensors: Advantages, challenges and future perspectives.Journal of electroanalytical chemistry (Lausanne, Switzerland) · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 2 institutions in 1 country.

Wioleta BiałobrzeskaInstitute of Biotechnology and Molecular Medicine, 3 Trzy Lipy St., 80-172 Gdansk, Poland.
Daniel FirganekInstitute of Biotechnology and Molecular Medicine, 3 Trzy Lipy St., 80-172 Gdansk, Poland.ORCID 0000-0002-8870-2714
Maciej CzerkiesInstitute of Fundamental Technological Research Polish Academy of Sciences, Pawińskiego 5B, 02-106 Warszawa, Poland.ORCID 0000-0001-9987-0783
Tomasz LipniackiInstitute of Fundamental Technological Research Polish Academy of Sciences, Pawińskiego 5B, 02-106 Warszawa, Poland.ORCID 0000-0002-3488-2561
Marta SkwareckaInstitute of Biotechnology and Molecular Medicine, 3 Trzy Lipy St., 80-172 Gdansk, Poland.
Karolina DziąbowskaInstitute of Biotechnology and Molecular Medicine, 3 Trzy Lipy St., 80-172 Gdansk, Poland.ORCID 0000-0002-0226-3635
Zofia CebulaInstitute of Biotechnology and Molecular Medicine, 3 Trzy Lipy St., 80-172 Gdansk, Poland.
Natalia MalinowskaSensDx, 14b Postępu St., 02-676 Warszawa, Poland.
Daniel BigusInstitute of Biotechnology and Molecular Medicine, 3 Trzy Lipy St., 80-172 Gdansk, Poland.ORCID 0000-0001-8477-3761
Ewelina BięgaInstitute of Biotechnology and Molecular Medicine, 3 Trzy Lipy St., 80-172 Gdansk, Poland.ORCID 0000-0002-2216-5493
Krzysztof PyrćMalopolska Centre of Biotechnology, Jagiellonian University, Gronostajowa 7, 30-387 Krakow, Poland.ORCID 0000-0002-3867-7688
Katarzyna PalaSensDx, 14b Postępu St., 02-676 Warszawa, Poland.
Sabina ŻołędowskaInstitute of Biotechnology and Molecular Medicine, 3 Trzy Lipy St., 80-172 Gdansk, Poland.
Dawid NidzworskiInstitute of Biotechnology and Molecular Medicine, 3 Trzy Lipy St., 80-172 Gdansk, Poland.
Institute of Fundamental Technological Research · PLJagiellonian University · PL

Funding

Narodowe Centrum Badań i Rozwoju TECHMATSTRATEG 1/347324/12/NCBR/2017Narodowe Centrum Nauki 2018/29/B/NZ2/00668
6 · The paper itself

Abstract

This paper presents the development and comparison of label-free electrochemical immunosensors based on screen-printed gold and glassy carbon (GC) disc electrodes for efficient and rapid detection of respiratory syncytial virus (RSV). Briefly, the antibody specific to the F protein of RSV was successfully immobilized on modified electrodes. Antibody coupling on the Au surface was conducted via 4-aminothiophenol (4-ATP) and glutaraldehyde (GA). The GC surface was modified with poly-L-lysine (PLL) for direct anti-RSV conjugation after EDC/NHS (1-Ethyl-3-(3-dimethylaminopropyl)carbodiimide/N-Hydroxysuccinimide) activation. Electrochemical characterizations of the immunosensors were carried out by cyclic voltammetry (CV) and electrochemical impedance spectroscopy (EIS). GC-based immunosensors show a dynamic range of antigen detection from 1.0 × 10

Indexed as

Biosensing TechniquesDielectric SpectroscopyElectrodesGoldLimit of DetectionMetal NanoparticlesRespiratory Syncytial VirusesGoldcyclic voltammetryelectrochemical impedance spectroscopyglassy carbongold electroderespiratory syncytial virussensor

Identifiers

PMID33202922
PMCPMC7698328
OpenAlexW3101586282

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.