Evidence map›Paper›PMID 33202911›Full record

ArticleInternational journal of molecular sciences2020

Revised Exon Structure of l-DOPA Decarboxylase (

Pinelopi I Artemaki, Maria Papatsirou, Michaela A Boti, Panagiotis G Adamopoulos, Spyridon Christodoulou, Dido Vassilacopoulou, Andreas Scorilas, Christos K Kontos

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.8field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 12 citations in OpenAlex.

  1. High Intratumoral i-tRF-GlyBiomedicines · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Pinelopi I ArtemakiDepartment of Biochemistry and Molecular Biology, Faculty of Biology, National and Kapodistrian University of Athens, 15701 Athens, Greece.
Maria PapatsirouDepartment of Biochemistry and Molecular Biology, Faculty of Biology, National and Kapodistrian University of Athens, 15701 Athens, Greece.
Michaela A BotiDepartment of Biochemistry and Molecular Biology, Faculty of Biology, National and Kapodistrian University of Athens, 15701 Athens, Greece.
Panagiotis G AdamopoulosDepartment of Biochemistry and Molecular Biology, Faculty of Biology, National and Kapodistrian University of Athens, 15701 Athens, Greece.
Spyridon ChristodoulouFourth Surgery Department, National and Kapodistrian University of Athens, University General Hospital "Attikon", 12462 Athens, Greece.
Dido VassilacopoulouDepartment of Biochemistry and Molecular Biology, Faculty of Biology, National and Kapodistrian University of Athens, 15701 Athens, Greece.
Andreas ScorilasDepartment of Biochemistry and Molecular Biology, Faculty of Biology, National and Kapodistrian University of Athens, 15701 Athens, Greece.ORCID 0000-0003-2427-4949
Christos K KontosDepartment of Biochemistry and Molecular Biology, Faculty of Biology, National and Kapodistrian University of Athens, 15701 Athens, Greece.ORCID 0000-0002-9935-8461
National and Kapodistrian University of Athens · GR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Colorectal cancer (CRC) is a highly heterogenous malignancy with an increased mortality rate. Aberrant splicing is a typical characteristic of CRC, and several studies support the prognostic value of particular transcripts in this malignancy. l-DOPA decarboxylase (DDC) and its derivative neurotransmitters play a multifaceted role in physiological and pathological states. Our recent data support the existence of 6

Indexed as

Alternative SplicingAromatic-L-Amino-Acid DecarboxylasesColorectal NeoplasmsExonsGene Expression Regulation, EnzymologicGene Expression Regulation, NeoplasticNeoplasm ProteinsCell Line, TumorDisease ProgressionHEK293 CellsHumansIsoenzymesTranscription, GeneticAromatic-L-Amino-Acid DecarboxylasesDDC protein, humanIsoenzymesNeoplasm Proteinsalternative splicingbiogenic aminescolon carcinomadopaminel-aromatic amino acid decarboxylase (AADC)molecular biomarkersnext-generation sequencing (NGS)protein isoformsserotonintranscriptomics

Identifiers

PMID33202911
PMCPMC7697000
OpenAlexW3102888453

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.