Evidence map›Paper›PMID 33202845›Full record

ArticleInternational journal of molecular sciences2020

Axon Injury-Induced Autophagy Activation Is Impaired in a

Su-Hyuk Ko, Gilberto Gonzalez, Zhijie Liu, Lizhen Chen

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of molecular sciences, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.7field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 5 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Su-Hyuk KoBarshop Institute for Longevity and Aging Studies, University of Texas Health Science Center at San Antonio, San Antonio, TX 78229, USA.ORCID 0000-0002-5008-0083
Gilberto GonzalezDepartment of Cell Systems and Anatomy, University of Texas Health Science Center at San Antonio, San Antonio, TX 78229, USA.
Zhijie LiuDepartment of Molecular Medicine, University of Texas Health Science Center at San Antonio, San Antonio, TX 78229, USA.
Lizhen ChenBarshop Institute for Longevity and Aging Studies, University of Texas Health Science Center at San Antonio, San Antonio, TX 78229, USA.
The University of Texas Health Science Center at San Antonio · US

Funding

CPRIT CPRIT RR160017NIH HHS NCI 1U54CA217297-01NIH HHS NIGMS R01GM137009
6 · The paper itself

Abstract

Autophagy is a conserved pathway that plays a key role in cell homeostasis in normal settings, as well as abnormal and stress conditions. Autophagy dysfunction is found in various neurodegenerative diseases, although it remains unclear whether autophagy impairment is a contributor or consequence of neurodegeneration. Axonal injury is an acute neuronal stress that triggers autophagic responses in an age-dependent manner. In this study, we investigate the injury-triggered autophagy response in a

Indexed as

Animals, Genetically ModifiedAutophagyAxonsCaenorhabditis elegansCaenorhabditis elegans ProteinsMicrotubule-Associated ProteinsAnimalsDisease Models, AnimalHumanstau ProteinsCaenorhabditis elegans ProteinsMAPT protein, humanMicrotubule-Associated ProteinsPTL-1 protein, C eleganstau Proteinsaggregationautophagyaxon injuryaxon regenerationptl-1Tautauopathy

Identifiers

PMID33202845
PMCPMC7696692
OpenAlexW3098612123

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.