Evidence map›Paper›PMID 33202777›Full record

ArticleMicroorganisms2020

Enteroviruses from Humans and Great Apes in the Republic of Congo: Recombination within Enterovirus C Serotypes.

Inestin Amona, Hacène Medkour, Jean Akiana, Bernard Davoust, Mamadou Lamine Tall, Clio Grimaldier, Celine Gazin, Christine Zandotti, Anthony Levasseur, Bernard La Scola and 4 more

Open access · goldAbstract read
In one paragraph

Article in Microorganisms, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.8field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 16 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Review
  6. Article
  7. Article
  8. Article
  9. Recombination in Positive-Strand RNA Viruses.Frontiers in microbiology · 2022
    Review
  10. Article
  11. Review
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 5 institutions in 3 countries.

Inestin AmonaIHU Méditerranée Infection, CEDEX 05, 13005 Marseille, France.
Hacène MedkourIHU Méditerranée Infection, CEDEX 05, 13005 Marseille, France.ORCID 0000-0002-5208-2576
Jean AkianaLaboratoire National de Santé Publique, Brazzaville, Congo.
Bernard DavoustIHU Méditerranée Infection, CEDEX 05, 13005 Marseille, France.ORCID 0000-0002-7836-6809
Mamadou Lamine TallIHU Méditerranée Infection, CEDEX 05, 13005 Marseille, France.ORCID 0000-0002-8949-104X
Clio GrimaldierIHU Méditerranée Infection, CEDEX 05, 13005 Marseille, France.
Celine GazinIHU Méditerranée Infection, CEDEX 05, 13005 Marseille, France.
Christine ZandottiIHU Méditerranée Infection, CEDEX 05, 13005 Marseille, France.
Anthony LevasseurIHU Méditerranée Infection, CEDEX 05, 13005 Marseille, France.
Bernard La ScolaIHU Méditerranée Infection, CEDEX 05, 13005 Marseille, France.ORCID 0000-0001-8006-7704
Didier RaoultIHU Méditerranée Infection, CEDEX 05, 13005 Marseille, France.
Florence FenollarIHU Méditerranée Infection, CEDEX 05, 13005 Marseille, France.
Henri Banga-MbokoEcole Nationale d'Agronomie et de Foresterie, Université Marien NGOUABI, Brazzaville, Congo.
Oleg MediannikovIHU Méditerranée Infection, CEDEX 05, 13005 Marseille, France.ORCID 0000-0001-6039-2008
Aix-Marseille Université · FRMéditerranée Infection Foundation · FRLaboratoire National de Santé Publique du Congo · CGMarien Ngouabi University · CGUniversity Frères Mentouri Constantine 1 · DZ

Funding

Institut Hospitalo-Universitaire (IHU) Méditerranée Infection NO
6 · The paper itself

Abstract

Enteroviruses (EVs) are viruses of the family Picornaviridae that cause mild to severe infections in humans and in several animal species, including non-human primates (NHPs). We conducted a survey and characterization of enteroviruses circulating between humans and great apes in the Congo. Fecal samples (N = 24) of gorillas and chimpanzees living close to or distant from humans in three Congolese parks were collected, as well as from healthy humans (N = 38) living around and within these parks. Enteroviruses were detected in 29.4% of gorilla and 13.15% of human feces, including wild and human-habituated gorillas, local humans and eco-guards. Two identical strains were isolated from two humans coming from two remote regions. Their genomes were similar and all genes showed their close similarity to coxsackieviruses, except for the 3C, 3D and 5'-UTR regions, where they were most similar to poliovirus 1 and 2, suggesting recombination. Recombination events were found between these strains, poliovirus 1 and 2 and EV-C99. It is possible that the same EV-C species circulated in both humans and apes in different regions in the Congo, which must be confirmed in other investigations. In addition, other studies are needed to further investigate the circulation and genetic diversity of enteroviruses in the great ape population, to draw a definitive conclusion on the different species and types of enteroviruses circulating in the Republic of Congo.

Indexed as

emergenceenterovirusgenetic recombinationhumansnon-human primatesRepublic of Congo

Identifiers

PMID33202777
PMCPMC7709013
OpenAlexW3102084929

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.