Evidence map›Paper›PMID 33202721›Full record

ArticleGenes2020

FLNC Expression Level Influences the Activity of TEAD-YAP/TAZ Signaling.

Anastasia Knyazeva, Aleksandr Khudiakov, Raquel Vaz, Aleksey Muravyev, Ksenia Sukhareva, Thomas Sejersen, Anna Kostareva

Open access · goldAbstract read
In one paragraph

Article in Genes, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
0.9field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
  2. Filamin C activates MAPK/ERK signaling to facilitate epithelial-mesenchymal transition in bladder cancer.Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2026
    Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. Genome-Wide Identification ofMarine drugs · 2023
    Article
  8. Review
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 3 countries.

Anastasia KnyazevaAlmazov National Medical Research Centre, 197341 Saint-Petersburg, Russia.
Aleksandr KhudiakovAlmazov National Medical Research Centre, 197341 Saint-Petersburg, Russia.ORCID 0000-0001-9214-0868
Raquel VazDepartment of Molecular Medicine and Surgery and Center for Molecular Medicine, Karolinska Institute, 171 76 Stockholm, Sweden.ORCID 0000-0001-7518-1801
Aleksey MuravyevAlmazov National Medical Research Centre, 197341 Saint-Petersburg, Russia.ORCID 0000-0003-0171-2475
Ksenia SukharevaAlmazov National Medical Research Centre, 197341 Saint-Petersburg, Russia.
Thomas SejersenDepartment of Women's and Children's Health, Karolinska Institute, 171 77 Stockholm, Sweden.
Anna KostarevaAlmazov National Medical Research Centre, 197341 Saint-Petersburg, Russia.
Federal Almazov North-West Medical Research Centre · RUKarolinska Institutet · SEUniversity of Verona · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Filamin C (FLNC), being one of the major actin-binding proteins, is involved in the maintenance of key muscle cell functions. Inherited skeletal muscle and cardiac disorders linked to genetic variants in

Indexed as

AcyltransferasesAdaptor Proteins, Signal TransducingAnimalsCell DifferentiationCell LineCell MovementCell ProliferationConnective Tissue Growth FactorFilaminsGene ExpressionGene Knockout TechniquesHippo Signaling PathwayMiceMuscle DevelopmentMyoblastsProtein Serine-Threonine KinasesAcyltransferasesAdaptor Proteins, Signal TransducingCCN2 protein, mouseConnective Tissue Growth FactorFilaminsProtein Serine-Threonine Kinasestafazzin protein, mouseYap1 protein, mouseYAP-Signaling ProteinsFLNCgenome editingHippo signalingmyogenic differentiation

Identifiers

PMID33202721
PMCPMC7696573
OpenAlexW3104786016

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.