Evidence map›Paper›PMID 33202696›Full record

ArticleMolecules (Basel, Switzerland)2020

Molecular Targets Implicated in the Antiparasitic and Anti-Inflammatory Activity of the Phytochemical Curcumin in Trichomoniasis.

Natalia Mallo, Jesús Lamas, Rosa Ana Sueiro, José Manuel Leiro

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
0.8field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 15 citations in OpenAlex.

  1. Review
  2. Review
  3. Potential of Curcumin in the Management of Skin Diseases.International journal of molecular sciences · 2024
    Review
  4. The neuroprotective potential of curcumin on T. Spiralis infected mice.BMC complementary medicine and therapies · 2024
    Article
  5. Article
  6. Article
  7. Article
  8. Review
  9. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Natalia MalloDepartment of Microbiology and Parasitology, Laboratory of Parasitology, Institute of Research on Chemical and Biological Analysis, Campus Vida, University of Santiago de Compostela, 15782 Santiago de Compostela, Spain.ORCID 0000-0002-2811-5788
Jesús LamasDepartment of Fundamental Biology, Institute of Aquaculture, Campus Vida, University of Santiago de Compostela, 15782 Santiago de Compostela, Spain.ORCID 0000-0002-9702-7140
Rosa Ana SueiroDepartment of Microbiology and Parasitology, Laboratory of Parasitology, Institute of Research on Chemical and Biological Analysis, Campus Vida, University of Santiago de Compostela, 15782 Santiago de Compostela, Spain.ORCID 0000-0002-3346-6670
José Manuel LeiroDepartment of Microbiology and Parasitology, Laboratory of Parasitology, Institute of Research on Chemical and Biological Analysis, Campus Vida, University of Santiago de Compostela, 15782 Santiago de Compostela, Spain.ORCID 0000-0001-6963-515X
Universidade de Santiago de Compostela · ES

Funding

Xunta de Galicia ED431C2017/31
6 · The paper itself

Abstract

Trichomoniasis, is the most prevalent non-viral sexually transmitted disease worldwide. Although metronidazole (MDZ) is the recommended treatment, several strains of the parasite are resistant to MDZ, and new treatments are required. Curcumin (CUR) is a polyphenol with anti-inflammatory, antioxidant and antiparasitic properties. In this study, we evaluated the effects of CUR on two biochemical targets: on proteolytic activity and hydrogenosomal metabolism in

Indexed as

Molecular Targeted TherapyAnimalsAnti-Inflammatory AgentsAntiparasitic AgentsCurcuminCytokinesGene Expression Regulation, EnzymologicInflammation MediatorsLipopolysaccharidesMacrophagesMembrane PotentialsMiceNitric OxideParasitesPhytochemicalsProteolysisAnti-Inflammatory AgentsAntiparasitic AgentsCurcuminCytokinesInflammation MediatorsLipopolysaccharidesNitric OxidePhytochemicalsPyruvate SynthaseRNA, Messengercurcuminhydrogenosomal enzymesproinflammatory cytokinesproteinasesTrichomonas vaginalis

Identifiers

PMID33202696
PMCPMC7697451
OpenAlexW3102036472

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.