Evidence map›Paper›PMID 33202685›Full record

ReviewInternational journal of environmental research and public health2020

The ECETOC-Targeted Risk Assessment Tool for Worker Exposure Estimation in REACH Registration Dossiers of Chemical Substances-Current Developments.

Jan Urbanus, Oliver Henschel, Qiang Li, Dave Marsh, Chris Money, Dook Noij, Paul van de Sandt, Joost van Rooij, Matthias Wormuth

Abstract readReview
In one paragraph

Review in International journal of environmental research and public health, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Jan UrbanusShell Health Risk Science Team, Belgian Shell N.V., B-1000 Brussels, Belgium.
Oliver HenschelCorporate Health Management, BASF SE, 67056 Ludwigshafen am Rhein, Germany.
Qiang LiClariant Produkte (Deutschland) GmbH, 65843 Sulzbach am Taunus, Germany.
Dave MarshExxonMobil Biomedical Sciences Inc, ExxonMobil, Leatherhead KT22 8UX, UK.
Chris MoneyCynara Consulting, Brockenhurst SO42 7RX, UK.ORCID 0000-0002-2428-5915
Dook NoijIn Personal Capacity, Formerly Dow Global Industrial Hygiene Expertise Centre, 4531 EB Terneuzen, The Netherlands.
Paul van de SandtShell Health Risk Science Team, Shell International B.V., 2596 HR The Hague, The Netherlands.
Joost van RooijCaesar Consult, 6503 CB Nijmegen, The Netherlands.
Matthias WormuthSyngenta Crop Protection AG, 4058 Basel, Switzerland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

(1) Background: The ECETOC Targeted Risk Assessment (TRA) tool is widely used for estimation of worker exposure levels in the development of dossiers for REACH registration of manufactured or imported chemical substances in Europe. A number of studies have been published since 2010 in which the exposure estimates of the tool are compared with workplace exposure measurement results and in some instances an underestimation of exposure was reported. The quality and results of these studies are being reviewed by ECETOC. (2) Methods: Original exposure measurement data from published comparison studies for which six or more data points were available for each workplace scenario and a TRA estimate had been developed to create a curated database to examine under what conditions and for which applications the tool is valid or may need adaptation. (3) Results: The published studies have been reviewed for completeness and clarity and TRA estimates have been constructed based on the available information, following a set of rules. The full review findings are expected to be available in the course of 2021. (4) Conclusions: The ECETOC TRA tool developers periodically review the validity and limitations of their tool, in line with international recommendations.

Indexed as

Occupational ExposureEnvironmental ExposureEuropeRisk Assessmentchemical regulationchemicalsexposure modellingoccupational exposure

Identifiers

PMID33202685
PMCPMC7697447

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.