Evidence map›Paper›PMID 33202681›Full record

ReviewMolecules (Basel, Switzerland)2020

Plant-Derived Natural Products in Cancer Research: Extraction, Mechanism of Action, and Drug Formulation.

Wamidh H Talib, Izzeddin Alsalahat, Safa Daoud, Reem Fawaz Abutayeh, Asma Ismail Mahmod

Abstract readReview
In one paragraph

Review in Molecules (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 54 papers.

0numbers the graph read from it
0cells of the map it votes in
54citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

54 citing papers in PubMed.

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  4. Cardiac Modulation byCurrent issues in molecular biology · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Wamidh H TalibDepartment of Clinical Pharmacy and Therapeutics, Applied Science Private University, Amman 11931, Jordan.ORCID 0000-0003-1942-8982
Izzeddin AlsalahatDepartment of Pharmaceutical Chemistry and Pharmacognosy, Applied Science Private University, Amman 11931, Jordan.
Safa DaoudDepartment of Pharmaceutical Chemistry and Pharmacognosy, Applied Science Private University, Amman 11931, Jordan.ORCID 0000-0003-1958-6534
Reem Fawaz AbutayehDepartment of Pharmaceutical Chemistry and Pharmacognosy, Applied Science Private University, Amman 11931, Jordan.ORCID 0000-0003-3895-2835
Asma Ismail MahmodDepartment of Clinical Pharmacy and Therapeutics, Applied Science Private University, Amman 11931, Jordan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cancer is one of the main causes of death globally and considered as a major challenge for the public health system. The high toxicity and the lack of selectivity of conventional anticancer therapies make the search for alternative treatments a priority. In this review, we describe the main plant-derived natural products used as anticancer agents. Natural sources, extraction methods, anticancer mechanisms, clinical studies, and pharmaceutical formulation are discussed in this review. Studies covered by this review should provide a solid foundation for researchers and physicians to enhance basic and clinical research on developing alternative anticancer therapies.

Indexed as

Drug CompoundingResearchAnimalsAntineoplastic AgentsBiological ProductsHumansNeoplasmsPlantsAntineoplastic AgentsBiological Productsalternative anticancer therapiescurcuminnatural productsplant extractsthymoquinon

Identifiers

PMID33202681
PMCPMC7696819

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.