Evidence map›Paper›PMID 33202652›Full record

ArticlePharmaceuticals (Basel, Switzerland)2020

Synthesis of New 1, 3, 4-Oxadiazole-Incorporated 1, 2, 3-Triazole Moieties as Potential Anticancer Agents Targeting Thymidylate Synthase and Their Docking Studies.

Mohammad Mahboob Alam, Abdulraheem Sa Almalki, Thikryat Neamatallah, Nada M Ali, Azizah M Malebari, Syed Nazreen

Open access · goldAbstract read
In one paragraph

Article in Pharmaceuticals (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
3.8field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 57 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Article
  5. Review
  6. Review
  7. Special Issue "Anticancer Drugs 2021".Pharmaceuticals (Basel, Switzerland) · 2022
    Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Mohammad Mahboob AlamDepartment of Chemistry, Faculty of Science, Albaha University, Albaha-1988, Saudi Arabia.
Abdulraheem Sa AlmalkiDepartment of Chemistry, Faculty of Science, Taif University, Taif-21974, Saudi Arabia.ORCID 0000-0002-6463-4163
Thikryat NeamatallahDepartment of Pharmacology and Toxicology, Faculty of Pharmacy, King Abdulaziz University, Jeddah 21589, Saudi Arabia.ORCID 0000-0002-2762-7108
Nada M AliDepartment of Chemistry, Faculty of Science, Albaha University, Albaha-1988, Saudi Arabia.
Azizah M MalebariDepartment of Pharmaceutical Chemistry, Faculty of Pharmacy, King Abdulaziz University, Jeddah 21589, Saudi Arabia.
Syed NazreenDepartment of Chemistry, Faculty of Science, Albaha University, Albaha-1988, Saudi Arabia.ORCID 0000-0002-5093-1538
Al Baha University · SAKing Abdulaziz University · SATaif University · SA

Funding

Taif University Researchers Supporting Project TURSP-2020/44
6 · The paper itself

Abstract

Thymidylate synthase (TS) has emerged as a hot spot in cancer treatment, as it is directly involved in DNA synthesis. In the present article, nine hybrids containing 1,2,3-triazole and 1,3,4-oxadiazole moieties (

Indexed as

1,2,3-triazole1,3,4-oxadiazole5-fluoruracilcytotoxicitydockingpemetrexedthymidylate synthase

Identifiers

PMID33202652
PMCPMC7696185
OpenAlexW3104581305

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.