Evidence map›Paper›PMID 33202597›Full record

ArticlePathogens (Basel, Switzerland)2020

Increased Prevalence of Liver Fibrosis and HIV Viremia among Patients with HIV, HBV, and Tuberculosis in Botswana.

Bonolo B Phinius, Motswedi Anderson, Lynnette Bhebhe, Kabo Baruti, Godiraone Manowe, Wonderful T Choga, Lucy Mupfumi, Tshepiso Mbangiwa, Mbatshi Mudanga, Sikhulile Moyo and 3 more

Abstract read
In one paragraph

Article in Pathogens (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. FibroScanMicroorganisms · 2024
    Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Bonolo B PhiniusResearch Laboratory, Botswana Harvard AIDS Institute Partnership, Gaborone 0000, Botswana.ORCID 0000-0002-0180-2705
Motswedi AndersonResearch Laboratory, Botswana Harvard AIDS Institute Partnership, Gaborone 0000, Botswana.ORCID 0000-0001-9974-9684
Lynnette BhebheResearch Laboratory, Botswana Harvard AIDS Institute Partnership, Gaborone 0000, Botswana.
Kabo BarutiResearch Laboratory, Botswana Harvard AIDS Institute Partnership, Gaborone 0000, Botswana.
Godiraone ManoweResearch Laboratory, Botswana Harvard AIDS Institute Partnership, Gaborone 0000, Botswana.
Wonderful T ChogaResearch Laboratory, Botswana Harvard AIDS Institute Partnership, Gaborone 0000, Botswana.ORCID 0000-0001-7606-0569
Lucy MupfumiResearch Laboratory, Botswana Harvard AIDS Institute Partnership, Gaborone 0000, Botswana.ORCID 0000-0002-2290-2481
Tshepiso MbangiwaResearch Laboratory, Botswana Harvard AIDS Institute Partnership, Gaborone 0000, Botswana.
Mbatshi MudangaResearch Laboratory, Botswana Harvard AIDS Institute Partnership, Gaborone 0000, Botswana.
Sikhulile MoyoResearch Laboratory, Botswana Harvard AIDS Institute Partnership, Gaborone 0000, Botswana.
Richard MarlinkRutgers Global Health Institute, Robert Wood Johnson Medical School, Rutgers University, New Brunswick, NJ 08901, USA.
Jason T BlackardDivision of Digestive Diseases, University of Cincinnati College of Medicine, Cincinnati, OH 45267, USA.ORCID 0000-0003-2876-3811
Simani GaseitsiweResearch Laboratory, Botswana Harvard AIDS Institute Partnership, Gaborone 0000, Botswana.

Funding

H3ABioNet U41HG006941Sub-Saharan African Network for TB/HIV Research Excellence (SANTHE) DEL-15-006Wellcome Trust 218770/Z/19/Z
6 · The paper itself

Abstract

People with concomitant human immunodeficiency virus (HIV) and tuberculosis (TB) have an increased risk of hepatotoxic reactions due to antiretroviral therapy (ART) and anti-TB therapy (ATT). Concomitant hepatitis B virus (HBV) in these patients may lead to poorer health outcomes. To assess liver enzyme levels and immune response in adults with HIV, HBV, and TB, data from 300 antiretroviral-naïve people living with HIV (PLWHIV) were analyzed. The prevalence of HIV/HBV (cHIV/HBV) and HIV/TB (cHIV/TB) was 28% (95% CI: 23.0-33.4) and 10% (95% CI: 6.8-14.0), respectively. HIV/HBV/TB (cHIV/HBV/TB) prevalence was 5.3% (95% CI: 3.1-8.5). There was a statistically significant difference between the groups of participants in HIV viral load (

Indexed as

AfricaBotswanahepatitis B virushuman immunodeficiency virustuberculosis

Identifiers

PMID33202597
PMCPMC7696587

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.