Evidence map›Paper›PMID 33202577›Full record

ArticleMolecules (Basel, Switzerland)2020

Monitoring Methylmalonic Aciduria by NMR Urinomics.

Alina Nicolescu, Daniela Blanita, Chiril Boiciuc, Victoria Hlistun, Mihaela Cristea, Dorina Rotaru, Ludmila Pinzari, Ana Oglinda, Adela Stamati, Isabela Tarcomnicu and 6 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Molecules (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Review
  3. A Real-Life Reproducibility Assessment for NMR Metabolomics.Diagnostics (Basel, Switzerland) · 2022
    Article
  4. Special Issue: NMR-Based Metabolomics.Molecules (Basel, Switzerland) · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Alina Nicolescu"Petru Poni" Institute of Macromolecular Chemistry, Romanian Academy, Aleea Grigore Ghica Voda 41A, RO-700487 Iasi, Romania.ORCID 0000-0001-7022-8893
Daniela BlanitaInstitute of Mother and Child, Str. Burebista 93, MD-2062 Chisinau, Moldova.
Chiril BoiciucInstitute of Mother and Child, Str. Burebista 93, MD-2062 Chisinau, Moldova.
Victoria HlistunInstitute of Mother and Child, Str. Burebista 93, MD-2062 Chisinau, Moldova.
Mihaela Cristea"Petru Poni" Institute of Macromolecular Chemistry, Romanian Academy, Aleea Grigore Ghica Voda 41A, RO-700487 Iasi, Romania.
Dorina Rotaru"Gheorghe Palade" City Clinical Hospital, Str. Melestiu 20, MD-2001 Chisinau, Moldova.
Ludmila PinzariInstitute of Mother and Child, Str. Burebista 93, MD-2062 Chisinau, Moldova.
Ana Oglinda"Nicolae Testemitanu" State University of Medicine and Pharmacy, Bd. Stefan cel Mare si Sfint 165, MD-2004 Chisinau, Moldova.
Adela Stamati"Nicolae Testemitanu" State University of Medicine and Pharmacy, Bd. Stefan cel Mare si Sfint 165, MD-2004 Chisinau, Moldova.
Isabela TarcomnicuCytogenomic Medical Laboratory, Calea Floreasca 35, RO-014453 Bucharest, Romania.ORCID 0000-0002-7439-2807
Andreea Tutulan-CunitaCytogenomic Medical Laboratory, Calea Floreasca 35, RO-014453 Bucharest, Romania.ORCID 0000-0002-5570-8749
Danae StambouliCytogenomic Medical Laboratory, Calea Floreasca 35, RO-014453 Bucharest, Romania.
Sergiu GladunInstitute of Mother and Child, Str. Burebista 93, MD-2062 Chisinau, Moldova.
Ninel Revenco"Nicolae Testemitanu" State University of Medicine and Pharmacy, Bd. Stefan cel Mare si Sfint 165, MD-2004 Chisinau, Moldova.
Natalia UşureluInstitute of Mother and Child, Str. Burebista 93, MD-2062 Chisinau, Moldova.
Calin Deleanu"Petru Poni" Institute of Macromolecular Chemistry, Romanian Academy, Aleea Grigore Ghica Voda 41A, RO-700487 Iasi, Romania.ORCID 0000-0001-8206-5227

Funding

Unitatea Executiva pentru Finantarea Invatamantului Superior, a Cercetarii, Dezvoltarii si Inovarii PN-III-P4-ID-PCCF-2016-0050 (5DnanoP)
6 · The paper itself

Abstract

The paper reports on monitoring methylmalonic aciduria (MMA)-specific and non-specific metabolites via NMR urinomics. Five patients have been monitored over periods of time; things involved were diet, medication and occasional episodes of failing to comply with prescribed diets. An extended dataset of targeted metabolites is presented, and correlations with the type of MMA are underlined. A survey of previous NMR studies on MMA is also presented.

Indexed as

Magnetic Resonance SpectroscopyMetabolomicsAmino Acid Metabolism, Inborn ErrorsChildChild, PreschoolCreatinineFemaleGlycineHumansInfantInfant, NewbornMaleTime FactorsCreatinineGlycinemetabolomicsmethylmalonic acidmethylmalonic aciduriaNMR spectroscopyurine

Identifiers

PMID33202577
PMCPMC7697698

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.