Evidence map›Paper›PMID 33202425›Full record

ArticleAmerican journal of perinatology2022

Rooming-in for Infants at Risk for Neonatal Abstinence Syndrome: Outcomes 5 Years following Its Introduction as the Standard of Care at One Hospital.

Adam Isaiah Newman, Dane Mauer-Vakil, Helen Coo, Lynn Newton, Emily Wilkerson, Sarah McKnight, Susan B Brogly

Abstract read
In one paragraph

Article in American journal of perinatology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

  1. Article
  2. Article
  3. Association between medication for opioid use disorder during pregnancy and neonatal outcomes.Journal of perinatology : official journal of the California Perinatal Association · 2026
    Article
  4. Article
  5. Review
  6. Review
  7. Prophylactic dextrose gel use in newborns at risk for hypoglycemia.Journal of perinatology : official journal of the California Perinatal Association · 2024
    Observational
  8. Review
  9. Prenatal Substance Exposure.Annual review of developmental psychology · 2023
    Article
  10. Article
  11. Article
  12. Article
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Adam Isaiah NewmanDepartment of Family Medicine, Queen's University, Kingston, Ontario, Canada.ORCID 0000-0002-4524-7264
Dane Mauer-VakilHealth Services Research Program, Dalla Lana School of Public Health, University of Toronto, Toronto, Ontario, Canada.
Helen CooDepartment of Pediatrics, Queen's University, Kingston, Ontario, Canada.
Lynn NewtonDepartment of Family Medicine, Queen's University, Kingston, Ontario, Canada.
Emily WilkersonSchool of Medicine, Queen's University, Kingston, Ontario, Canada.
Sarah McKnightDepartment of Pediatrics, Queen's University, Kingston, Ontario, Canada.
Susan B BroglyDepartment of Surgery, Queen's University, Kingston, Ontario, Canada.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThe practice of rooming-in for opioid-dependent infants was introduced as the standard of care at our hospital following a pilot study which demonstrated that such infants had shorter lengths of stay and were less likely to require pharmacological treatment. We sought to determine whether these benefits have continued, and whether outcomes support continuing to use rooming-in as standard care. STUDY

designOpioid-dependent infants delivered at 36 weeks gestation or later between January 1, 2015, and December 31, 2019, were eligible for rooming-in. Charts were reviewed and data were extracted regarding maternal and infant conditions, whether neonatal pharmacological treatment was required, and total length of hospital stay. Outcomes were compared with two historical groups reported in a previous pilot study: 24 healthy near-term opioid-dependent newborns who were admitted directly to the neonatal intensive care unit (NICU) prior to the introduction of rooming-in (May 1, 2012-May 31, 2013), and 20 similar opioid-dependent infants who were the first to room-in at our hospital (September 1, 2013-September 30, 2014).

resultsOnly 3.5% of 57 infants who roomed-in during the 5-year study period required pharmacological treatment, compared with 15% who roomed-in during the first year of the program's introduction and 83.3% who had been admitted directly to the NICU. The median length of stay remained 5 days for infants rooming-in, compared with 24 days for opioid-dependent infants in the cohort admitted to the NICU.

conclusionEarly observations of the benefits of rooming-in on neonatal outcomes were sustained. Infants allowed to room-in were significantly less likely to require initiation of pharmacotherapy and a prolonged hospital stay than similar infants prior to the implementation of rooming-in as standard care. A large proportion of the infants who might have benefited from rooming-in required admission to the NICU for reasons other than neonatal abstinence syndrome (NAS). KEY POINTS: · Benefits of rooming-in for near-term opioid-dependent infants were sustained or increased.. · Rooming-in is sustainable as standard care for these newborns.. · Many infants required admission to NICU for reasons other than NAS..

Indexed as

Neonatal Abstinence SyndromeAnalgesics, OpioidChildHospitalsHumansInfantInfant, NewbornIntensive Care Units, NeonatalLength of StayPilot ProjectsRooming-in CareStandard of CareAnalgesics, Opioid

Identifiers

PMID33202425
PMCPMC9270102

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.