SynthesisSpecial care in dentistry : official publication of the American Association of Hospital Dentists, the Academy of Dentistry for the Handicapped, and the American Society for Geriatric Dentistry2020
Clinical practice guidelines: Oral health care for children and adults living with epidermolysis bullosa.
Synthesis in Special care in dentistry : official publication of the American Association of Hospital Dentists, the Academy of Dentistry for the Handicapped, and the American Society for Geriatric Dentistry, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05288478 (Phase II Dose-ranging Study of Dentoxol® Mouthrinse for Managing Oral Symptoms in Epidermolysis Bullosa.), which is not on this map. Cited by 32 papers, 5 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Phase II Dose-ranging Study of Dentoxol® Mouthrinse for Managing Oral Symptoms in Epidermolysis Bullosa.
Who cites it
32 citing papers in PubMed, 5 syntheses or guidelines pooled it, 74 citations in OpenAlex.
- Management of oesophageal strictures in inherited epidermolysis bullosa: a clinical practice guideline.The British journal of dermatology · 2025Guideline
- Consensus-based guidelines for the provision of palliative and end-of-life care for people living with epidermolysis bullosa.Orphanet journal of rare diseases · 2023Guideline
- Recommendations on pregnancy, childbirth and aftercare in epidermolysis bullosa: a consensus-based guideline.The British journal of dermatology · 2022Guideline
- Clinical practice guidelines: Oral health care for children and adults living with epidermolysis bullosa.Special care in dentistry : official publication of the American Association of Hospital Dentists, the Academy of Dentistry for the Handicapped, and the American Society for Geriatric Dentistry · 2020Pooled it
- Orthodontic Treatment in Patients With Epidermolysis Bullosa (EB)-Clinical Practice Guidelines (CPG).Special care in dentistry : official publication of the American Association of Hospital Dentists, the Academy of Dentistry for the Handicapped, and the American Society for Geriatric DentistryGuideline
- Dentofacial Characteristics in Patients With Epidermolysis Bullosa-A Cross-Sectional Study.Clinical and experimental dental research · 2026Article
- Epidermolysis Bullosa Classification and Current Approach to Diagnosis.Pediatric dermatology · 2026Review
- Barriers, Benefits and Complications of Orthodontic Treatment in Patients with Epidermolysis Bullosa: A Patient-Reported Cross-Sectional Study.Healthcare (Basel, Switzerland) · 2026Article
- Oral Manifestations in Different Subtypes of Hereditary Epidermolysis Bullosa: A Retrospective Case Series From an Asian Cohort.Oral diseases · 2026Article
- Oral status and dental treatment needs in patients with Epidermolysis Bullosa - a cross-sectional study.Clinical oral investigations · 2026Article
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- Editorial: Transforming special care dentistry: frameworks for education, clinical excellence and technological innovation.Frontiers in oral health · 2026Article
- Oral health status, treatment needs and oral health-related quality of life in patients with epidermolysis bullosa in Austria: a mixed-methods pilot study.Frontiers in oral health · 2026Article
- Oral health of patients with epidermolysis bullosa compared to healthy controls - a retrospective study from a specialized center.BMC oral health · 2025Article
- An International Online Survey on Oral Hygiene Issues in Patients with Epidermolysis Bullosa.Dentistry journal · 2025Article
- Dental Implant Therapy in Patients With Autoimmune Diseases: A Scoping Review.Clinical oral implants research · 2025Article
- Health challenges and importance of using photobiomodulation therapy in patients with epidermolysis bullosa: a cross-sectional study.Lasers in medical science · 2025Article
- Oral health care pathways for patients with epidermolysis bullosa: A position statement from the European reference network for rare skin diseases.Journal of the European Academy of Dermatology and Venereology : JEADV · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
22 authors at 14 institutions in 9 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundInherited epidermolysis bullosa (EB) is a genetic disorder characterized by skin fragility and unique oral features.
aimsTo provide (a) a complete review of the oral manifestations in those living with each type of inherited EB, (b) the current best practices for managing oral health care of people living with EB, (c) the current best practices on dental implant-based oral rehabilitation for patients with recessive dystrophic EB (RDEB), and (d) the current best practice for managing local anesthesia, principles of sedation, and general anesthesia for children and adults with EB undergoing dental treatment.
methodsSystematic literature search, panel discussion including clinical experts and patient representatives from different centers around the world, external review, and guideline piloting.
resultsThis article has been divided into five chapters: (i) general information on EB for the oral health care professional, (ii) systematic literature review on the oral manifestations of EB, (iii) oral health care and dental treatment for children and adults living with EB-clinical practice guidelines, (iv) dental implants in patients with RDEB-clinical practice guidelines, and (v) sedation and anesthesia for adults and children with EB undergoing dental treatment-clinical practice guidelines. Each chapter provides recommendations on the management of the different clinical procedures within dental practice, highlighting the importance of patient-clinician partnership, impact on quality of life, and the importance of follow-up appointments. Guidance on the use on nonadhesive wound care products and emollients to reduce friction during patient care is provided.
conclusionsOral soft and hard tissue manifestations of inherited EB have unique patterns of involvement associated with each subtype of the condition. Understanding each subtype individually will help the professionals plan long-term treatment approaches.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.