Evidence map›Paper›PMID 33201951›Full record

ArticleSoft matter2021

Combined electrokinetic and shear flows control colloidal particle distribution across microchannel cross-sections.

Varun Lochab, Shaurya Prakash

Abstract read
In one paragraph

Article in Soft matter, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Varun LochabDepartment of Mechanical and Aerospace Engineering, The Ohio State University, Columbus, OH 43210, USA. prakash.31@osu.edu.ORCID http://orcid.org/0000-0003-3923-1968
Shaurya PrakashDepartment of Mechanical and Aerospace Engineering, The Ohio State University, Columbus, OH 43210, USA. prakash.31@osu.edu.ORCID http://orcid.org/0000-0002-5263-0843

Funding

Translational Therapeutics Research Program (TT)P30CA016058 · NCI · OHIO STATE UNIVERSITY · PI Jennifer A. Woyach · 1985 to 2026
$132.3M
Biophysical-based approach for controlling blood vessel structure and functionR01HL141941 · NHLBI · OHIO STATE UNIVERSITY · PI CASTRO, CARLOS E., PRAKASH, SHAURYA · 2018 to 2021
$2.0M
NCI NIH HHS P30 CA016058NHLBI NIH HHS R01 HL141941
6 · The paper itself

Abstract

Recent experimental observations on combined electrokinetic and shear flows of colloidal suspensions in rectangular cross-section microfluidic channels have shown unusual cross-stream colloidal particle migration and dynamic assembly. Although a new electrophoresis-induced lift force has been postulated to cause the lateral migration of colloidal particles, little is known about how fluid properties and flow conditions impact this force and therefore subsequent colloidal particle migration. Furthermore, no experimental quantification of this electrophoresis-induced lift force is available. We report several key advances by demonstrating that the kinematic viscosity of the fluid can be used to modulate the spatial distribution of particles over the entire microchannel cross-section, with suppression of the colloidal particle migration observed with increase in fluid kinematic viscosity. Colloidal particle migration of ∼10 μm from not only the top and bottom microchannel walls but also from the side walls is shown with the corresponding electrophoresis-induced lift force of up to ∼30 fN. The breadth of flow conditions tested capture the channel Reynolds number in the 0.1-1.1 range, with inertial migration of colloidal particles shown in flow regimes where the migration was previously thought to be ineffective, if not for the electrophoresis-induced lift force. The ability of the electrophoresis-induced lift force to migrate colloidal particles across the entire microchannel cross-section establishes a new paradigm for three-dimensional control of colloidal particles within confined microchannels.

Identifiers

PMID33201951
PMCPMC7855569

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.