ArticleSports health
Quadriceps Strength and Kinesiophobia Predict Long-Term Function After ACL Reconstruction: A Cross-Sectional Pilot Study.
Article in Sports health. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 2 of them syntheses that pooled it.
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Who cites it
19 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Kinesiophobia, Knee Self-Efficacy, and Fear Avoidance Beliefs in People with ACL Injury: A Systematic Review and Meta-Analysis.Sports medicine (Auckland, N.Z.) · 2022Pooled it
- Pooled it
- ACL injury reprograms quadriceps myonuclear epigenetic and transcriptional signatures in mice.Molecular medicine (Cambridge, Mass.) · 2026Article
- Muscle atrophy after ACL reconstruction involves molecular mechanisms beyond unloading.Journal of applied physiology (Bethesda, Md. : 1985) · 2026Article
- An Examination of the Relationship Between Fear of Reinjury and Neuromuscular, Musculoskeletal, and Biomechanical Characteristics at the Time of Return to Sport following Anterior Cruciate Ligament Reconstruction.International journal of sports physical therapy · 2026Article
- CSF1-R inhibition attenuates posttraumatic osteoarthritis and quadriceps atrophy following ligament injury.The Journal of physiology · 2025Article
- The impact of exercise therapy on rehabilitation outcomes after anterior cruciate ligament reconstruction: a network meta-analysis.BMC musculoskeletal disorders · 2025Article
- Interpreting Quadriceps Strength Thresholds for Patients Following ACL-Reconstruction: A Clinical Commentary.International journal of sports physical therapy · 2025Article
- Sedentary Behavior Patterns After ACL Reconstruction.International journal of exercise science · 2025Article
- Overexpression of manganese superoxide dismutase mitigates ACL injury-induced muscle atrophy, weakness and oxidative damage.Free radical biology & medicine · 2024Article
- Vitamin D status associates with skeletal muscle loss after anterior cruciate ligament reconstruction.JCI insight · 2023Article
- GDF8 inhibition enhances musculoskeletal recovery and mitigates posttraumatic osteoarthritis following joint injury.Science advances · 2023Article
- Factors Associated With Long-Term Quadriceps Muscle Function After Surgical Fixation of Lower Extremity Fractures.Physical therapy · 2023Article
- Evidence Review for Preventing Osteoarthritis After an Anterior Cruciate Ligament Injury: An Osteoarthritis Action Alliance Consensus Statement.Journal of athletic training · 2023Article
- Contributors to self-report motor function after anterior cruciate ligament reconstruction.Scientific reports · 2023Article
- The Comparison of Psychological Barriers Between Individuals with a History of Anterior Knee Pain, Anterior Cruciate Ligament Reconstruction, and Healthy Individuals.International journal of sports physical therapy · 2023Article
- Evaluation of the Back-in-Action test Battery In Uninjured High School American Football Players.International journal of sports physical therapy · 2023Article
- Current study on the influence of psychological factors on returning to sports after ACLR.Heliyon · 2022Review
- Differences in Gait Biomechanics Between Adolescents and Young Adults With Anterior Cruciate Ligament Reconstruction.Journal of athletic training · 2022Article
Corrections and comments
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Authors and funding
7 authors.
Funding
Abstract
backgroundMany patients live with long-term deficits in knee function after an anterior cruciate ligament reconstruction (ACLR). However, research is inconclusive as to which physical performance measure is most strongly related to long-term patient-reported outcomes after ACLR. HYPOTHESIS: Quadriceps strength would be most strongly associated with patient-reported long-term outcomes after ACLR. STUDY
designCross-sectional study. LEVEL OF EVIDENCE: Level 3.
methodsA total of 40 patients (29 female) consented and participated an average of 10.9 years post-ACLR (range, 5-20 years). Patients completed the Lower Extremity Functional Scale (LEFS), the International Knee Documentation Committee (IKDC) Scale, Knee injury and Osteoarthritis Outcome Score Quality of Life (KOOS QoL) and Sport (KOOS Sport) subscales, and the Tampa Scale of Kinesiophobia (TSK-17). Each patient subsequently performed maximal isometric quadriceps contraction, a 60-second single-leg step-down test, and the single-leg single hop and triple hop for distance tests. Multivariate linear and logistic regression models determined how performance testing was associated with each patient-reported outcome when controlling for time since surgery, age, and TSK-17.
resultsWhen controlling for time since surgery, age at the time of consent, and TSK-17 score, maximal isometric quadriceps strength normalized to body weight was the sole physical performance measure associated with IKDC (
conclusionIsometric quadriceps strength and kinesiophobia are significantly associated with long-term patient-reported outcomes after ACLR. CLINICAL RELEVANCE: These results suggest that training to improve quadriceps strength and addressing kinesiophobia in the late stages of recovery from ACLR may improve long-term self-reported function.
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