ArticleMolecular plant pathology2021
Microtubule-assisted mechanism for toxisome assembly in Fusarium graminearum.
Article in Molecular plant pathology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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Who cites it
7 citing papers in PubMed, 19 citations in OpenAlex.
- Pilot-scale fermentation to produce trichodiene, a fungal volatile that suppresses trichothecene production in mycotoxigenic fungi.Applied and environmental microbiology · 2026Article
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- Advances in UnderstandingGenes · 2024Review
- The Microtubule End Binding Protein Mal3 Is Essential for the Dynamic Assembly of Microtubules duringInternational journal of molecular sciences · 2024Article
- Vacuole Proteins with Optimized Microtubule Assembly Is Required for Fum1 Protein Localization and Fumonisin Biosynthesis in Mycotoxigenic FungusJournal of fungi (Basel, Switzerland) · 2023Article
- Functional Roles of αApplied and environmental microbiology · 2021Article
- Microtubule-assisted mechanism for toxisome assembly in Fusarium graminearum.Molecular plant pathology · 2021Article
Corrections and comments
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Authors and funding
7 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
In Fusarium graminearum, a trichothecene biosynthetic complex known as the toxisome forms ovoid and spherical structures in the remodelled endoplasmic reticulum (ER) under mycotoxin-inducing conditions. Previous studies also demonstrated that disruption of actin and tubulin results in a significant decrease in deoxynivalenol (DON) biosynthesis in F. graminearum. However, the functional association between the toxisome and microtubule components has not been clearly defined. In this study we tested the hypothesis that the microtubule network provides key support for toxisome assembly and thus facilitates DON biosynthesis. Through fluorescent live cell imaging, knockout mutant generation, and protein-protein interaction assays, we determined that two of the four F. graminearum tubulins, α
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Registered trials
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