Evidence map›Paper›PMID 33201450›Full record

ArticleMaternal and child health journal2021

Antenatal Care Visit Attendance Frequency and Birth Outcomes in Rural Uganda: A Prospective Cohort Study.

Rachel P McDiehl, Adeline A Boatin, Godfrey R Mugyenyi, Mark J Siedner, Laura E Riley, Joseph Ngonzi, Lisa M Bebell

Open access · greenAbstract read
In one paragraph

Article in Maternal and child health journal, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 1 pooled it
3.9field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 1 synthesis or guideline pooled it, 31 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Exploring the experiences of adolescent primigravidae during their first antenatal care visit in Gauteng Province.South African family practice : official journal of the South African Academy of Family Practice/Primary Care · 2026
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  11. Associations between Antenatal Care Visit Attendance and Infant Mortality and Growth.The American journal of tropical medicine and hygiene · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 2 countries.

Rachel P McDiehlEmory University School of Medicine Department of Gynecology and Obstetrics, Glenn Building, 4th Floor - 412B, 69 Jesse Hill Jr Drive SE, Atlanta, GA, 30303, USA. Rachel.mcdiehl@emory.edu.
Adeline A BoatinMassachusetts General Hospital Department of Obstetrics and Gynecology, 55 Fruit St, Boston, MA, 02114, USA.
Godfrey R MugyenyiMbarara University of Science and Technology Department of Obstetrics and Gynaecology, P.O. Box 1410, Mbarara, Uganda.
Mark J SiednerMassachusetts General Hospital Center for Global Health, Suite 722, 125 Nashua St, Boston, MA, 02114, USA.
Laura E RileyWeill Cornell Medical Center Department of Obstetrics and Gynecology, New York, NY, USA.
Joseph NgonziMbarara University of Science and Technology Department of Obstetrics and Gynaecology, P.O. Box 1410, Mbarara, Uganda.
Lisa M BebellMassachusetts General Hospital Center for Global Health, Suite 722, 125 Nashua St, Boston, MA, 02114, USA.ORCID http://orcid.org/0000-0003-0077-6522
Massachusetts General Hospital · USMbarara University of Science and Technology · UGCornell University · USEmory University · US

Funding

PROGRAM FOR AIDS CLINICAL RESEARCH TRAINING (PACRT)T32AI007433 · NIAID · MASSACHUSETTS GENERAL HOSPITAL · PI MARK J SIEDNER · 1992 to 2026
$11.4M
Institutional Career Development CoreKL2TR002542 · NCATS · HARVARD MEDICAL SCHOOL · PI BREDELLA, MIRIAM ANTOINETTE, RUTKOVE, SEWARD B. · 2018 to 2022
$8.7M
Vanderbilt-Emory-Cornell-Duke Consortium for Global Health Fellows (VECDor)R25TW009337 · FIC · VANDERBILT UNIVERSITY MEDICAL CENTER · PI HEIMBURGER, DOUGLAS CORBETT, VERMUND, STEN H. · 2012 to 2016
$6.3M
HIV Infection, Placental Inflammation, and Early Childhood Outcomes in HIV-exposed, Uninfected Infants in UgandaK23AI138856 · NIAID · MASSACHUSETTS GENERAL HOSPITAL · PI BEBELL, LISA M · 2019 to 2023
$1.1M
American Society of Tropical Medicine and Hygiene ASTMH/BWF FellowshipCharles H. Hood Foundation FellowshipFIC NIH HHS R25 TW009337FIC NIH HHS T32AI007433Harvard Global Health Institute FellowshipInfectious Diseases Society of America Medical Student Scholars ProgramNational Institute of Allergy and Infectious Diseases K23AI138856NCATS NIH HHS KL2 TR002542NIAID NIH HHS K23 AI138856NIAID NIH HHS T32 AI007433NIH HHS R25 TW009337
6 · The paper itself

Abstract

objectivesAntenatal care (ANC) is designed to improve pregnancy outcomes by providing screening and treatment for preventable and treatable diseases. However, data are lacking on whether ANC affects stillbirth risk. We hypothesized stillbirth risk in Uganda is lower in women attending the recommended ≥ 4 ANC visits compared to those attending ≤ 3.

methodsWe performed a secondary analysis of subset of 1,785 women enrolled in a prospective cohort of postpartum infection who presented to a regional referral hospital for delivery. Our primary outcome was documented stillbirth; a secondary composite poor birth outcome included stillbirth, early neonatal death, low birth weight (< 2500 g), and 5-min APGAR score < 7. We performed multivariable logistic regression analyses to identify independent correlates of stillbirth and poor birth outcome.

resultsOf 1,785 participants, 58 (3%) pregnancies resulted in stillbirth and 198 (11%) had a poor birth outcome. Of 1,236 women attending ≥ 4 ANC visits, 31 (2.5%) had a stillbirth, compared to 27/510 (5.2%) attending ≤ 3. In multivariable analyses controlling for age, parity, distance traveled, referral status to hospital, malaria prophylaxis, and syphilis infection; attending ≥ 4 ANC visits was associated with significantly reduced odds of stillbirth (aOR 0.5, 95% CI 0.3-0.9, P = 0.02) and poor birth outcome (aOR 0.66, 95% CI 0.4-0.96, P = 0.03). Malaria prophylaxis was also independently associated with reduced odds of stillbirth (aOR 0.05, 95% CI 0.2-1.0, P = 0.04).

conclusionsAttending ≥ 4 ANC visits was associated with reduced odds of stillbirth and poor birth outcomes in this Ugandan cohort, which may be related to more comprehensive infection screening, treatment, and prevention services.

Indexed as

AdultAmbulatory Care FacilitiesCohort StudiesFemaleHumansInfant, NewbornPerinatal DeathPregnancyPregnancy OutcomePremature BirthPrenatal CareProspective StudiesResidence CharacteristicsRural PopulationStillbirthUgandaAntenatal careNeonatal deathResource-limited settingStillbirthUganda

Identifiers

PMID33201450
PMCPMC7878332
OpenAlexW3099228755

What OpenQuestion holds

Textmetadata
LicenceTDM
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.