Evidence map›Paper›PMID 33201441›Full record

ArticleIndian journal of gastroenterology : official journal of the Indian Society of Gastroenterology2020

Utility of bowel ultrasound in assessing disease activity in Crohn's disease.

Pradeep Kakkadasam Ramaswamy, Kayal Vizhi N, Amit Yelsangikar, Anupama Nagar Krishnamurthy, Vinay Bhat, Naresh Bhat

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Article in Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
1.8field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 20 citations in OpenAlex.

  1. Beyond bowel wall thickness: Is the international bowel ultrasound segmental activity score ready for prime time in Crohn's disease?Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology · 2026
    Article
  2. Diagnostic accuracy of the international bowel ultrasound segmental activity score for assessing disease activity in Crohn's disease.Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology · 2026
    Article
  3. Article
  4. Correlation of Point-of-Care Intestinal Ultrasound With Endoscopic Disease Severity in Crohn's Disease.JGH open : an open access journal of gastroenterology and hepatology · 2025
    Article
  5. Using ultrasonographic features in pediatric Crohn's disease activity index severity.International journal of physiology, pathophysiology and pharmacology · 2025
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  12. Indian Journal of Gastroenterology September-October 2020.Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology · 2020
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Pradeep Kakkadasam RamaswamyDepartment of Gastroenterology, Liver Diseases and Clinical Nutrition, Aster CMI Hospital, #43/2, International Airport Road, Sahakar Nagar, Bangalore, 560 092, India. drkrpradeep@gmail.com.ORCID http://orcid.org/0000-0003-2608-4401
Kayal Vizhi NDepartment of Gastroenterology, Liver Diseases and Clinical Nutrition, Aster CMI Hospital, #43/2, International Airport Road, Sahakar Nagar, Bangalore, 560 092, India.
Amit YelsangikarDepartment of Gastroenterology, Liver Diseases and Clinical Nutrition, Aster CMI Hospital, #43/2, International Airport Road, Sahakar Nagar, Bangalore, 560 092, India.
Anupama Nagar KrishnamurthyDepartment of Gastroenterology, Liver Diseases and Clinical Nutrition, Aster CMI Hospital, #43/2, International Airport Road, Sahakar Nagar, Bangalore, 560 092, India.
Vinay BhatDepartment of Surgery and Allied Sciences, Aster CMI Hospital, Bangalore 560 092, India.
Naresh BhatDepartment of Gastroenterology, Liver Diseases and Clinical Nutrition, Aster CMI Hospital, #43/2, International Airport Road, Sahakar Nagar, Bangalore, 560 092, India.
ISCO International (United States) · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundGastrointestinal ultrasound (GIUS) has been used increasingly for monitoring inflammatory bowel disease (IBD) patients. The aim of this study was to assess the utility of GIUS in assessing disease activity in Crohn's disease (CD).

methodsConsecutive patients with CD (diagnosis established for at least 6 months) between July 2017 and July 2018 requiring assessment of disease activity were prospectively assessed by magnetic resonance enterography, colonoscopy (CS), and GIUS within a 2-week period and without any change in ongoing treatment. Features on GIUS which correlated with disease activity were assessed. Sensitivity and specificity of the GIUS in assessing disease activity and localization were calculated.

resultsThirty-five patients were enrolled in the study. Bowel wall thickness (BWT) ≥ 3 mm and Doppler activity ≥ 2 had the highest sensitivity (100% and 95.6%, respectively) for detecting active disease on CS. BWT ≥ 3 mm had sensitivity, specificity, positive predictive value, and negative predictive value of 100%, 83.3%, 92%, and 100%, respectively for assessing active disease. Combination of median BWT, Doppler activity, and loss of bowel wall stratification correlated with simplified endoscopic score (SES) for CD (r = 0.8, p 0.009) and Harvey-Bradshaw index (HBI, r = 0.76, p 0.04). For localizing active disease in the ileum, GIUS had a sensitivity of 93.7%, 80% for lesions in the right colon, 100% for transverse colon, and 89% for the left colon. Specificity was 100% for ileal and colonic lesions.

conclusionLoss of stratification, BWT, and Doppler activity in the bowel wall correlate with endoscopic and clinical disease activity in CD. GIUS is a sensitive modality in assessing disease activity in CD.

Indexed as

Crohn DiseaseFemaleHumansIntestinesMalePredictive Value of TestsSensitivity and SpecificitySeverity of Illness IndexTime FactorsUltrasonographyBiosimilarsBowel ultrasoundCalprotectinCrohn’s diseaseCrohn’s disease activity indexHarvey Bradshaw scoreInflammatory bowel diseaseMucosal healingSimplified endoscopic score

Identifiers

PMID33201441
OpenAlexW3102084235

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.