Evidence map›Paper›PMID 33201339›Full record

ArticleJournal of mathematical neuroscience2020

Interactions of multiple rhythms in a biophysical network of neurons.

Alexandros Gelastopoulos, Nancy J Kopell

Open access · hybridAbstract read
In one paragraph

Article in Journal of mathematical neuroscience, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.1field-weighted citation impact, top 55% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Noninvasive inference methods for interaction and noise intensities of coupled oscillators using only spike time data.Proceedings of the National Academy of Sciences of the United States of America · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 2 countries.

Alexandros GelastopoulosDepartment of Mathematics and Statistics, Boston University, 111 Cummington Mall, 02215, Boston, MA, USA. gelas@bu.edu.ORCID http://orcid.org/0000-0003-1428-0130
Nancy J KopellDepartment of Mathematics and Statistics, Boston University, 111 Cummington Mall, 02215, Boston, MA, USA.
Boston University · US

Funding

National Science Foundation DMS-1225647National Science Foundation DMS-1514796
6 · The paper itself

Abstract

Neural oscillations, including rhythms in the beta1 band (12-20 Hz), are important in various cognitive functions. Often neural networks receive rhythmic input at frequencies different from their natural frequency, but very little is known about how such input affects the network's behavior. We use a simplified, yet biophysical, model of a beta1 rhythm that occurs in the parietal cortex, in order to study its response to oscillatory inputs. We demonstrate that a cell has the ability to respond at the same time to two periodic stimuli of unrelated frequencies, firing in phase with one, but with a mean firing rate equal to that of the other. We show that this is a very general phenomenon, independent of the model used. We next show numerically that the behavior of a different cell, which is modeled as a high-dimensional dynamical system, can be described in a surprisingly simple way, owing to a reset that occurs in the state space when the cell fires. The interaction of the two cells leads to novel combinations of properties for neural dynamics, such as mode-locking to an input without phase-locking to it.

Indexed as

Neural oscillationsPhase-lockingPhase-response curveState resetTime-division multiplexing

Identifiers

PMID33201339
PMCPMC7671958
OpenAlexW3099495247

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.