ArticleScandinavian journal of work, environment & health2021
Effect of long work hours and shift work on high-sensitivity C-reactive protein levels among Korean workers.
Article in Scandinavian journal of work, environment & health, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.
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Who cites it
19 citing papers in PubMed, 1 synthesis or guideline pooled it, 18 citations in OpenAlex.
- Associations of working conditions and chronic low-grade inflammation among employees: a systematic review and meta-analysis.Scandinavian journal of work, environment & health · 2021Pooled it
- Psychological stress during medical internship is associated with inflammatory signatures linked to mental health.Brain, behavior, & immunity - health · 2026Article
- The mediating effect of immune-inflammatory indices in shift work and hypertension: a cohort study in China.Scandinavian journal of work, environment & health · 2026Article
- Differential Intestinal Epithelial Injury Following Passive and Exertional Hyperthermia.Sports medicine - open · 2026Article
- Circadian disruption and circulating TGF-β1 in workers: evidence from Mendelian randomization and observational data.Frontiers in immunology · 2026Observational
- Occupational Risk Factors for Kidney Disease: A Comprehensive Review.Journal of Korean medical science · 2025Review
- Overwork and changes in brain structure: a pilot study.Occupational and environmental medicine · 2025Article
- Research advances inAnimal nutrition (Zhongguo xu mu shou yi xue hui) · 2025Review
- The association between precarious employment and stress among working aged individuals in the United States.Preventive medicine · 2024Article
- [Overwork induces vascular endothelial barrier dysfunction in mice].Nan fang yi ke da xue xue bao = Journal of Southern Medical University · 2024Article
- Working hours and cardiovascular disease.Scandinavian journal of work, environment & health · 2024Article
- A multiscale inflammatory map: linking individual stress to societal dysfunction.Frontiers in science · 2024Article
- Shiftwork, long working hours and markers of inflammation in a national US population-based sample of employed black and white men and women aged ≥45 years.Occupational and environmental medicine · 2023Article
- Associations between circadian disruption and cardiometabolic disease risk: A review.Obesity (Silver Spring, Md.) · 2023Review
- Occupational Health Aspects with Special Focus on Physiological Differences between Office and Metalworkers.Antioxidants (Basel, Switzerland) · 2022Article
- Cohort study of long working hours and increase in blood high-sensitivity C-reactive protein (hsCRP) concentration: Mechanisms of overwork and cardiovascular disease.Journal of occupational health · 2022Article
- Working for Long Hours Is Associated With Dietary Fiber Insufficiency.Frontiers in nutrition · 2022Article
- Presenteeism and Productivity: The Role of Biomarkers and Hormones.International journal of environmental research and public health · 2021Article
- A longitudinal study of working hours and chronic kidney disease in healthy workers: The Kangbuk Samsung Health Study.Journal of occupational health · 2021Article
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Objective We aimed to investigate the association between low-grade inflammation as indicated by high-sensitivity C-reactive protein (hsCRP) level and organizational factors, such as work hours and shift work. Methods We evaluated 7470 young and middle-aged workers who participated in the Korea National Health and Nutrition Examination Surveys from 2015-2018. Work hours were determined from self-reported questionnaires. Shift work was defined as a non-daytime fixed work schedule. An interaction effect between shift work and long work hours on the hsCRP level was estimated using relative excess risk due to interaction (RERI) and attributable proportion (AP) with 95% confidence intervals (CI). Results Increased hsCRP levels were prevalent in 25.2% of the study population. There was a significant association between long work hours and increased hsCRP, especially among middle-aged men [odds ratio (OR) 1.50 (95% CI 1.20-1.87) for moderately increased hsCRP and OR 1.62 (95% CI 1.14-2.30) for highly increased hsCRP]. There was a significant interaction effect between long work hours and shift work on increased hsCRP among middle-aged workers. The RERI were 0.03 (95% CI 0.02-0.04) and 0.56 (95% CI 0.45-0.68) among middle-aged men and women, respectively. The AP were 0.02 (95% CI 0.01-0.03) and 0.36 (95% CI 0.31-0.40) among middle-aged men and women, respectively. Conclusion There was no significant association between shift work and the level of hsCRP. Long work hours were related to low-grade inflammatory processes, but only in middle-aged workers. There was an interaction effect between long work hours and shift work for increased hsCRP, especially in middle-aged women.
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