Evidence map›Paper›PMID 33200089›Full record

ArticleInformatics in medicine unlocked2020

A multiple peptides vaccine against COVID-19 designed from the nucleocapsid phosphoprotein (N) and Spike Glycoprotein (S) via the immunoinformatics approach.

Sahar Obi Abd Albagi, Mosab Yahya Al-Nour, Mustafa Elhag, Asaad Tageldein Idris Abdelihalim, Esraa Musa Haroun, Mohammed Elmujtba Adam Essa, Mustafa Abubaker, Hemchandra Deka, Arabinda Ghosh, Mohammed A Hassan

Open access · goldAbstract read
In one paragraph

Article in Informatics in medicine unlocked, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.0field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 17 citations in OpenAlex.

  1. Article
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  8. Review
  9. Lessons Learned from Cutting-Edge Immunoinformatics on Next-Generation COVID-19 Vaccine Research.International journal of peptide research and therapeutics · 2021
    Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 8 institutions in 3 countries.

Sahar Obi Abd AlbagiDepartment of Microbiology and Immunology, AL Neelain University, Khartoum, Sudan.
Mosab Yahya Al-NourDepartment of Pharmaceutical Chemistry, Faculty of Pharmacy, Omdurman Islamic University, Khartoum, Sudan.
Mustafa ElhagFaculty of Medicine, University of Seychelles-American Institute of Medicine, Seychelles.
Asaad Tageldein Idris AbdelihalimClinical Immunology Council, Sudan Medical Specialization Board, Sudan.
Esraa Musa HarounFaculty of Medical Pharmacology, Ahfad University for Women, Sudan.
Mohammed Elmujtba Adam EssaDepartment of Clinical Medical, Medical and Cancer Research Institute, Nyala, Sudan.
Mustafa AbubakerFaculty of Medical Laboratory Sciences, Sudan University of Science and Technology, Sudan.
Hemchandra DekaDepartment of Bioengineering and Technology, GUIST, Gauhati University, Guwahati, Assam, India.
Arabinda GhoshMicrobiology Division, Department of Botany, Gauhati University, Guwahati, Assam, India.
Mohammed A HassanDepartment of Bioinformatics, DETAGEN Genetics Diagnostic Center, Kayseri, Turkey.
Gauhati University · INAhfad University for Women · SDAl-Neelain University · SDOmdurman Islamic University · SDSudan Medical Specialization Board · SDSudan University of Science and Technology · SDUniversity of Nyala · SDUniversity of Seychelles · SC

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Due to the current Coronavirus (COVID-19) pandemic, the rapid discovery of a safe and effective vaccine is an essential issue. Consequently, this study aims to predict a potential COVID-19 peptide-based vaccine utilizing the Nucleocapsid phosphoprotein (N) and Spike Glycoprotein (S) via the Immunoinformatics approach. To achieve this goal, several Immune Epitope Database (IEDB) tools, molecular docking, and safety prediction servers were used. According to the results, The Spike peptide

Indexed as

And immunoinformaticsCOVID-19Multiple peptides vaccineNucleocapsidSpike

Identifiers

PMID33200089
PMCPMC7654333
OpenAlexW3105759195

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.