ArticleTranslational vision science & technology2020
Combined Multi-Modal Assessment of Glaucomatous Damage With Electroretinography and Optical Coherence Tomography/Angiography.
Article in Translational vision science & technology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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Who cites it
11 citing papers in PubMed, 16 citations in OpenAlex.
- Acute Effects of Oral Caffeine Intake on Human Global-Flash mfERG Responses: A Placebo-Controlled, Double-Masked, Balanced Crossover Study.Investigative ophthalmology & visual science · 2024Trial
- Comparison of Microvascular and Electrophysiological Findings of Normal-Tension Glaucoma and Chronic Non-Arteritic Ischemic Optic Neuropathies.Turkish journal of ophthalmology · 2025Article
- DTL versus skin electrodes in recording of multifocal pattern electroretinogram and multifocal photopic negative response.Documenta ophthalmologica. Advances in ophthalmology · 2025Article
- The diagnostic accuracy of photopic negative responses evoked by broadband and chromatic stimuli in a clinically heterogeneous population.Documenta ophthalmologica. Advances in ophthalmology · 2023Article
- Retinal Vessel Caliber Measurement Bias in Fundus Images in the Presence of the Central Light Reflex.Translational vision science & technology · 2023Article
- Functional and structural readouts for early detection of retinal involvement in multiple sclerosis.Frontiers in integrative neuroscience · 2023Article
- Retinal Oxygen Delivery and Extraction in Ophthalmologically Healthy Subjects With Different Blood Pressure Status.Translational vision science & technology · 2022Article
- U-Shaped Effect of Blood Pressure on Structural OCT Metrics and Retinal Perfusion in Ophthalmologically Healthy Subjects.Investigative ophthalmology & visual science · 2021Article
- Non-invasive electrophysiology in glaucoma, structure and function-a review.Eye (London, England) · 2021Review
- The role of pattern electroretinograms and optical coherence tomography angiography in the diagnosis of normal-tension glaucoma.Scientific reports · 2021Article
- Comparison of the Humphrey Field Analyzer and Photopic Negative Response of Focal Macular Electroretinograms in the Evaluation of the Relationship Between Macula Structure and Function.Frontiers in medicine · 2021Article
Corrections and comments
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Authors and funding
5 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Purpose: To compare the diagnostic performance and to evaluate the interrelationship of electroretinographical and structural and vascular measures in glaucoma. Methods: For 14 eyes of 14 healthy controls and 15 eyes of 12 patients with glaucoma ranging from preperimetric to advanced stages optical coherence tomography (OCT), OCT-angiography (OCT-A), and electrophysiological measures (multifocal photopic negative response ratio [mfPhNR] and steady-state pattern electroretinography [ssPERG]) were applied to assess changes in retinal structure, microvasculature, and function, respectively. The diagnostic performance was assessed via area-under-curve (AUC) measures obtained from receiver operating characteristics analyses. The interrelation of the different measures was assessed with correlation analyses. Results: The mfPhNR, ssPERG amplitude, parafoveal (pfVD) and peripapillary vessel density (pVD), macular ganglion cell inner plexiform layer thickness (mGCIPL) and peripapillary retinal nerve fiber layer thickness (pRNFL) were significantly reduced in glaucoma. The AUC for mfPhNR was highest among diagnostic modalities (AUC: 0.88, 95% confidence interval: 0.75-1.0, Conclusions: The combination of ERG measures and OCT-A improved diagnostic performance and enhanced understanding of pathophysiology in glaucoma. Translational Relevance: Multimodal assessment of glaucoma damage improves diagnostics and monitoring of disease progression.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.